The modulation of brain function via the application of weak direct current was first observed
directly in the early 19th century. In the past 3 decades, transcranial magnetic stimulation …

The human default network (DN) plays a critical role in internally directed cognition,
behavior, and neuropsychiatric disease. Despite much progress with functional …

The basal ganglia, thalamus, and cerebral cortex form an interconnected network implicated
in many neurological and psychiatric illnesses. A better understanding of cortico-subcortical …

Intracranial electrical stimulation (iES) of the human brain has long been known to elicit a
remarkable variety of perceptual, motor and cognitive effects, but the functional–anatomical …

At the group-level, deep brain stimulation leads to significant therapeutic benefit in a
multitude of neurological and neuropsychiatric disorders. At the single-patient level …

Neuroimaging has seen a paradigm shift away from a formal description of local activity
patterns towards studying distributed brain networks. The recently defined framework of the …

Treatment-resistant obsessive-compulsive disorder (OCD) occurs in approximately one-third
of OCD patients. Obsessions may fluctuate over time but often occur or worsen in the …

Background Multiple deep brain stimulation (DBS) targets have been proposed for treating
intractable obsessive-compulsive disorder (OCD). Here, we investigated whether stimulation …

Parkinson's disease (PD) is a neurodegenerative disorder characterized by the
degeneration of dopaminergic neurons and/or loss od neuronal projections, in several …

Obsessive-compulsive disorder (OCD) is a neuropsychiatric disorder featuring repetitive
intrusive thoughts and behaviors associated with a significant handicap. Of patients, 20 …