Alzheimer's disease (AD) is a complex neurodegenerative disorder that affects multiple
brain regions and is difficult to treat. In this study we used 22 AD large-scale gene …

Mitochondria account for essential cellular pathways, from ATP production to nucleotide
metabolism, and their deficits lead to neurological disorders and contribute to the onset of …

Single-cell RNA sequencing (scRNA-seq) is a widely used technique for characterizing
individual cells and studying gene expression at the single-cell level. Clustering plays a vital …

Simple Summary Neurodevelopmental disorders are typically attributed to abnormal brain
development. These disorders encompass a wide range of neuropsychiatric symptoms that …

Developmental neuron death plays a pivotal role in refining organization and wiring during
neocortex formation. Aberrant regulation of this process results in neurodevelopmental …

Adverse childhood experiences (ACEs, ie, abuse, neglect, household dysfunction) represent
a potential risk factor for a wide range of long-lasting diseases and shorter life expectancy …

The intellectual disability (ID) in Down syndrome (DS) is thought to result from a variety of
developmental deficits such as alterations in neural progenitor division, neurogenesis …

Mutations in ARID1B, a member of the mSWI/SNF complex, cause severe
neurodevelopmental phenotypes with elusive mechanisms in humans. The most common …

Human's robust cognitive abilities, including creativity and language, are made possible, at
least in large part, by evolutionary changes made to the cerebral cortex. This paper reviews …

Functioning of the nervous system requires proper formation and specification of neurons as
well as accurate connectivity and signalling between them. Locomotor behaviour depends …