RNA helicases of the DEAD box family are present in all eukaryotic cells and in many
bacteria and Archaea. These highly conserved enzymes are required for RNA metabolism …

RNA helicases are ubiquitous, highly conserved enzymes that participate in nearly all
aspects of RNA metabolism. These proteins bind or remodel RNA or RNA–protein …

Superfamily 2 helicase proteins are ubiquitous in RNA biology and have an extraordinarily
broad set of functional roles. Central among these roles are the promotion of …

DEAD-box helicases perform diverse cellular functions in virtually all steps of RNA
metabolism from Bacteria to Humans. Although DEAD-box helicases share a highly …

Superfamily 1 and superfamily 2 RNA helicases are ubiquitous messenger-RNA–protein
complex (mRNP) remodelling enzymes that have critical roles in all aspects of RNA …

Translational repression and mRNA degradation are critical mechanisms of
posttranscriptional gene regulation that help cells respond to internal and external cues. In …

In eukaryotic organisms, the orthologs of the DEAD-box RNA helicase Ded1p from yeast
and DDX3 from human form a well-defined subfamily that is characterized by high sequence …

Hepatitis C virus non-structural protein 3 contains a serine protease and an RNA helicase.
Protease cleaves the genome-encoded polyprotein and inactivates cellular proteins …

DEAD‐box proteins are ubiquitous in RNA‐mediated processes and function by coupling
cycles of ATP binding and hydrolysis to changes in affinity for single‐stranded RNA. Many …

Superfamily 2 helicases are involved in all aspects of RNA metabolism, and many steps in
DNA metabolism. This review focuses on the basic mechanistic, structural and biological …