De novo design and structural characterization of proteins and metalloproteins

WF DeGrado, CM Summa, V Pavone… - Annual review of …, 1999 - annualreviews.org
▪ Abstract De novo protein design has recently emerged as an attractive approach for
studying the structure and function of proteins. This approach critically tests our …

From molecules to materials: Current trends and future directions

P Alivisatos, PF Barbara, AW Castleman… - Advanced …, 1998 - Wiley Online Library
The development, characterization, and exploitation of novel materials based on the
assembly of molecular components is an exceptionally active and rapidly expanding field …

De novo proteins as models of radical enzymes

C Tommos, JJ Skalicky, DL Pilloud, AJ Wand… - Biochemistry, 1999 - ACS Publications
Catalytically essential side-chain radicals have been recognized in a growing number of
redox enzymes. Here we present a novel approach to study this class of redox cofactors. Our …

Solvent as electron donor: donor/acceptor electronic coupling is a dynamical variable

EW Castner, D Kennedy, RJ Cave - The Journal of Physical …, 2000 - ACS Publications
We combine analysis of measurements by femtosecond optical spectroscopy, computer
simulations, and the generalized Mulliken− Hush (GMH) theory in the study of electron …

Multifaceted aspects of charge transfer

JB Derr, J Tamayo, JA Clark, M Morales… - Physical Chemistry …, 2020 - pubs.rsc.org
Charge transfer and charge transport are by far among the most important processes for
sustaining life on Earth and for making our modern ways of living possible. Involving multiple …

Comparison of the binding of cadmium (II), mercury (II), and arsenic (III) to the de novo designed peptides TRI L12C and TRI L16C

M Matzapetakis, BT Farrer, TC Weng… - journal of the …, 2002 - ACS Publications
Designed α-helical peptides of the TRI family with a general sequence Ac-G (LKALEEK) 4G-
CONH2 were used as model systems for the study of metal− protein interactions. Variants …

Theories of structure–function relationships for bridge-mediated electron transfer reactions

SS Skourtis, DN Beratan - Advances in Chemical Physics …, 2007 - books.google.com
C. Orthogonal Basis D. The Two-State Approximation 1. Partitioning the Many-electron
Green Function III. One-Dimensional Models and Analytical Solutions A. Perturbative …

Electron transfer across helical peptides

N Amdursky - ChemPlusChem, 2015 - Wiley Online Library
Electron transfer (ET) across proteins is one of the fundamental processes in nature. While
trying to decipher and understand natural ET, much scientific effort has been employed in …

Binding acceleration techniques for the detection of analytes

G Blackburn, JG Vielmetter, JF Kayyem - US Patent 7,087,148, 2006 - Google Patents
2001-05-07 Assigned to CLINICAL MICRO SENSORS, INC. reassignment CLINICAL
MICRO SENSORS, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT …

Understanding metalloprotein folding using a de novo design strategy

D Ghosh, VL Pecoraro - Inorganic chemistry, 2004 - ACS Publications
Metal ions play significant roles in most biological systems. Over the past two decades, there
has been significant interest in the redesign of existing metal binding sites in …