The role of extracellular vesicles in cancer

R Kalluri, KM McAndrews - Cell, 2023 - cell.com
Intercellular communication is a key feature of cancer progression and metastasis.
Extracellular vesicles (EVs) are generated by all cells, including cancer cells, and recent …

Extracellular signals regulate the biogenesis of extracellular vesicles

Y Jin, L Ma, W Zhang, W Yang, Q Feng, H Wang - Biological Research, 2022 - Springer
Extracellular vesicles (EVs) are naturally released membrane vesicles that act as carriers of
proteins and RNAs for intercellular communication. With various biomolecules and specific …

Anticancer therapy targeting cancer-derived extracellular vesicles

X Cheng, BS Henick, K Cheng - ACS nano, 2024 - ACS Publications
Extracellular vesicles (EVs) are natural lipid nanoparticles secreted by most types of cells. In
malignant cancer, EVs derived from cancer cells contribute to its progression and metastasis …

Interaction network of extracellular vesicles building universal analysis via eye tears: iNEBULA

L Hu, X Liu, Q Zheng, W Chen, H Xu, H Li, J Luo… - Science …, 2023 - science.org
Discovering the secrets of diseases from tear extracellular vesicles (EVs) is well-recognized
and appreciated. However, a precise understanding of the interaction network between EV …

Plasma versus serum for extracellular vesicle (EV) isolation: A duel for reproducibility and accuracy for CNS‐originating EVs biomarker analysis

HB Taha - Journal of Neuroscience Research, 2023 - Wiley Online Library
Blood‐derived extracellular vesicles (EVs) are a popular source of biomarkers for central
nervous system (CNS) diseases, but inconsistencies in isolation and analysis hinder their …

Exosome-bearing hydrogels and cardiac tissue regeneration

H Amini, AR Namjoo, MT Narmi, N Mardi… - Biomaterials …, 2023 - spj.science.org
Background In recent years, cardiovascular disease in particular myocardial infarction (MI)
has become the predominant cause of human disability and mortality in the clinical setting …

Extracellular vesicles and their cells of origin: Open issues in autoimmune diseases

A Haghighitalab, M Dominici, MM Matin… - Frontiers in …, 2023 - frontiersin.org
The conventional therapeutic approaches to treat autoimmune diseases through
suppressing the immune system, such as steroidal and non-steroidal anti-inflammatory …

Engineered exosomes as drug and RNA co-delivery system: new hope for enhanced therapeutics?

H Chen, H Yao, J Chi, C Li, Y Liu, J Yang… - … in Bioengineering and …, 2023 - frontiersin.org
Chemotherapy often faces some obstacles such as low targeting effects and drug
resistance, which introduce the low therapeutic efficiency and strong side effects. Recent …

Circadian rhythms in cardiovascular metabolism

H Lal, SK Verma, Y Wang, M Xie… - Circulation Research, 2024 - Am Heart Assoc
Energetic demand and nutrient supply fluctuate as a function of time-of-day, in alignment
with sleep-wake and fasting-feeding cycles. These daily rhythms are mirrored by 24-hour …

Rapid and in‐depth proteomic profiling of small extracellular vesicles for ultralow samples

J Cross, A Rai, H Fang, B Claridge, DW Greening - Proteomics, 2024 - Wiley Online Library
The integration of robust single‐pot, solid‐phase‐enhanced sample preparation with
powerful liquid chromatography‐tandem mass spectrometry (LC‐MS/MS) is routinely used …