Advances in drug delivery systems, challenges and future directions

TC Ezike, US Okpala, UL Onoja, CP Nwike, EC Ezeako… - Heliyon, 2023 - cell.com
Advances in molecular pharmacology and an improved understanding of the mechanism of
most diseases have created the need to specifically target the cells involved in the initiation …

Zero-order drug delivery: State of the art and future prospects

ML Laracuente, HY Marina, KJ McHugh - Journal of Controlled Release, 2020 - Elsevier
Pharmaceutical drugs are an important part of the global healthcare system, with some
estimates suggesting over 50% of the world's population takes at least one medication per …

Progress in brain targeting drug delivery system by nasal route

AR Khan, M Liu, MW Khan, G Zhai - Journal of Controlled Release, 2017 - Elsevier
The blood–brain barrier (BBB) restricts the transport of potential therapeutic moieties to the
brain. Direct targeting the brain via olfactory and trigeminal neural pathways by passing the …

External triggering and triggered targeting strategies for drug delivery

Y Wang, DS Kohane - Nature Reviews Materials, 2017 - nature.com
Drug delivery systems that are externally triggered to release drugs and/or target tissues
hold considerable promise for improving the treatment of many diseases by minimizing …

The significance of artificial intelligence in drug delivery system design

P Hassanzadeh, F Atyabi, R Dinarvand - Advanced drug delivery reviews, 2019 - Elsevier
Over the last decade, increasing interest has been attracted towards the application of
artificial intelligence (AI) technology for analyzing and interpreting the biological or genetic …

Materials and device design for advanced phototherapy systems

JS Lee, J Kim, Y Ye, T Kim - Advanced Drug Delivery Reviews, 2022 - Elsevier
Phototherapy has recently emerged as a promising solution for cancer treatment due to its
multifunctionality and minimal invasiveness. Notwithstanding the limited penetration depth of …

Design and fabrication of drug‐delivery systems toward adjustable release profiles for personalized treatment

A Geraili, M Xing, K Mequanint - View, 2021 - Wiley Online Library
Advanced polymeric controlled delivery systems are designed to effectively treat chronic
diseases by adjusting the temporal profile of drug release. Most conventional controlled …

Advances in molecularly imprinted polymers as drug delivery systems

R Liu, A Poma - Molecules, 2021 - mdpi.com
Despite the tremendous efforts made in the past decades, severe side/toxic effects and poor
bioavailability still represent the main challenges that hinder the clinical translation of drug …

Hydrogel-forming microneedles for rapid and efficient skin deposition of controlled release tip-implants

K Peng, LK Vora, J Domínguez-Robles… - Materials Science and …, 2021 - Elsevier
In this work, we introduce, for the first time, novel hybrid microneedle patches with
implantable poly (lactic-co-glycolic acid)(PLGA) tips aligned with hydrogel-forming …

AI-powered blockchain technology for public health: A contemporary review, open challenges, and future research directions

R Kumar, Arjunaditya, D Singh, K Srinivasan, YC Hu - Healthcare, 2022 - mdpi.com
Blockchain technology has been growing at a substantial growth rate over the last decade.
Introduced as the backbone of cryptocurrencies such as Bitcoin, it soon found its application …