Advanced atomic force microscopy modes for biomedical research

F Xia, K Youcef-Toumi - Biosensors, 2022 - mdpi.com
Visualization of biomedical samples in their native environments at the microscopic scale is
crucial for studying fundamental principles and discovering biomedical systems with …

A look into the use of Raman spectroscopy for brain and breast cancer diagnostics: linear and non-linear optics in cancer research as a gateway to tumor cell identity

H Abramczyk, B Brozek-Pluska, A Jarota… - Expert review of …, 2020 - Taylor & Francis
Introduction: Currently, intensely developing of linear and non-linear optical methods for
cancer detection provides a valuable tool to improve sensitivity and specificity. One of the …

Simultaneous co-localized super-resolution fluorescence microscopy and atomic force microscopy: combined SIM and AFM platform for the life sciences

AI Gómez-Varela, DR Stamov, A Miranda, R Alves… - Scientific reports, 2020 - nature.com
Correlating data from different microscopy techniques holds the potential to discover new
facets of signaling events in cellular biology. Here we report for the first time a hardware set …

Correlative Fluorescence and Transmission Electron Microscopy Assisted by 3D Machine Learning Reveals Thin Nanodiamonds Fluoresce Brighter

H Wen, D Kordahl, IC Kuschnerus, P Reineck… - ACS …, 2023 - ACS Publications
Nitrogen vacancy (NV) centers in fluorescent nanodiamonds (FNDs) draw widespread
attention as quantum sensors due to their room-temperature luminescence, exceptional …

Infrared scattering-type scanning near-field optical microscopy of biomembranes in water

E Pfitzner, J Heberle - The Journal of Physical Chemistry Letters, 2020 - ACS Publications
Infrared (IR) absorption spectroscopy detects the state and chemical composition of
biomolecules solely by their inherent vibrational fingerprints. Major disadvantages like the …

Recent advances in bioimaging with high-speed atomic force microscopy

T Uchihashi, C Ganser - Biophysical Reviews, 2020 - Springer
Among various microscopic techniques for characterizing protein structures and functions,
high-speed atomic force microscopy (HS-AFM) is a unique technique in that it allows direct …

Tip-enhanced Raman spectroscopy with amplitude-controlled tapping-mode AFM

T Umakoshi, K Kawashima, T Moriyama, R Kato… - Scientific Reports, 2022 - nature.com
Tip-enhanced Raman spectroscopy (TERS) is a powerful tool for analyzing chemical
compositions at the nanoscale owing to near-field light localized at a metallic tip. In TERS …

In Situ Real-Time Observation of Photoinduced Nanoscale Azo-Polymer Motions Using High-Speed Atomic Force Microscopy Combined with an Inverted Optical …

K Yang, FY Chan, H Watanabe, S Yoshioka… - Nano Letters, 2024 - ACS Publications
High-speed atomic force microscopy (HS-AFM) is an indispensable technique in the field of
biology owing to its imaging capability with high spatiotemporal resolution. Furthermore …

Synchronous, crosstalk-free correlative AFM and confocal microscopies/spectroscopies

TFD Fernandes, O Saavedra-Villanueva, E Margeat… - Scientific Reports, 2020 - nature.com
Microscopies have become pillars of our characterization tools to observe biological
systems and assemblies. Correlative and synchronous use of different microscopies relies …

Microscopic residual oil distribution characteristics and quantitative characterization of producing degree based on core fluorescence analysis technology

H Xia, L Wang, P Han, R Cao, S Zhang, X Sun - Geofluids, 2021 - Wiley Online Library
In this study, to address the insufficiency of research on the distribution characteristics and
quantitative characterization of oil, water, and rock in a reservoir, laser confocal and core …