Abstract Purpose of Review Hyperlipidemia is the major cardiovascular morbidity and
mortality risk factor. Statins are the first-line treatment for hyperlipidemia. Statin-associated …

Lipid disorders are the most common risk factor for atherosclerotic cardiovascular disease
(ASCVD). Statins are the gold standard in the treatment of lipid disorders. These drugs …

Genetic factors are recognized as risk factors for statin-associated muscle symptoms
(SAMS), which are the most common cause of statin intolerance. The aim of this study was to …

Background To determine the effect of genetic polymorphism of drug transporters on the
efficacy of treatment with Rosuvastatin, Atorvastatin and Simvastatin in patients with …

Objectives Statins represent an important pharmacological factor for the prevention of
cardiovascular diseases but may also cause severe cases of myotoxicity. Numerous studies …

Cardiovascular diseases are the leading cause of morbidity and mortality worldwide.
Effective medications for the treatment of cardiovascular diseases include antithrombotic …

Pharmacogenomics is considered the most widely relevant and feasible genomics
application in clinical medicine [1]. Growing knowledge of drug–gene associations …

Introduction: Medicines with high toxicity profiles have a heightened risk of causing serious
and fatal adverse drug effects (ADEs). General Practice (GP) is key in identifying and …

Adverse drug reactions (ADRs) are a major health concern and represent an important
cause of morbidity and mortality worldwide. The factors affecting the risk of ADR are multiple …

The following codes for treatments and procedures applicable to this guideline are included
below for informational purposes. Inclusion or exclusion of a procedure, diagnosis or device …