Neuropathic pain is a chronic secondary pain condition, which is a consequence of
peripheral or central nervous (somatosensory) system lesions or diseases. It is a devastating …

The intervertebral disc (IVD) is the most avascular and acellular tissue in the body and
therefore prone to degeneration. During IVD degeneration, the balance between anabolic …

Although cervical radicular pain is a major cause of disability, no studies have been
published comparing different types of nonsurgical therapy. This multi-institutional …

As the population ages, spine-related pain is increasingly common in older adults. While
medications play an important role in pain management, their use has limitations in geriatric …

These consensus guidelines aim to provide an overview of best practice for managing
chronic spinal pain reflecting the heterogeneity of low back pain. Most guidelines have …

The aim of this study was to establish the somatosensory profiles of patients with cervical
radiculopathy and patients with nonspecific neck–arm pain associated with heightened …

Pregabalin is a commonly used therapy currently recommended as first‐line treatment for a
number of neuropathic pain (NeP) conditions. Since licensure, a number of clinical trials of …

Objective. Rheumatologic disorders are associated with sleep disturbances. This study
examines sleep disturbance correlates in patients with SSc. Methods. Participants are 180 …

Pregabalin is approved for the treatment of a variety of clinical conditions and its analgesic,
anxiolytic and anticonvulsant properties are well documented. Pregabalin's effects on sleep …

Introduction Mirogabalin, which is a selective ligand of the α 2 δ subunit of voltage-gated Ca
2+ channels, was recently approved in Japan for peripheral neuropathic pain. The α 2 δ …