Molecular components of the Mammalian circadian clock
ED Buhr, JS Takahashi - Circadian clocks, 2013 - Springer
Mammals synchronize their circadian activity primarily to the cycles of light and darkness in
the environment. This is achieved by ocular photoreception relaying signals to the …
the environment. This is achieved by ocular photoreception relaying signals to the …
Circadian integration of metabolism and energetics
J Bass, JS Takahashi - Science, 2010 - science.org
Circadian clocks align behavioral and biochemical processes with the day/night cycle.
Nearly all vertebrate cells possess self-sustained clocks that couple endogenous rhythms …
Nearly all vertebrate cells possess self-sustained clocks that couple endogenous rhythms …
Central and peripheral circadian clocks in mammals
JA Mohawk, CB Green… - Annual review of …, 2012 - annualreviews.org
The circadian system of mammals is composed of a hierarchy of oscillators that function at
the cellular, tissue, and systems levels. A common molecular mechanism underlies the cell …
the cellular, tissue, and systems levels. A common molecular mechanism underlies the cell …
Genetics of circadian rhythms in Mammalian model organisms
PL Lowrey, JS Takahashi - Advances in genetics, 2011 - Elsevier
The mammalian circadian system is a complex hierarchical temporal network which is
organized around an ensemble of uniquely coupled cells comprising the principal circadian …
organized around an ensemble of uniquely coupled cells comprising the principal circadian …
Regulating the suprachiasmatic nucleus (SCN) circadian clockwork: interplay between cell-autonomous and circuit-level mechanisms
ED Herzog, T Hermanstyne… - Cold Spring …, 2017 - cshperspectives.cshlp.org
The suprachiasmatic nucleus (SCN) is the principal circadian clock of the brain, directing
daily cycles of behavior and physiology. SCN neurons contain a cell-autonomous …
daily cycles of behavior and physiology. SCN neurons contain a cell-autonomous …
Genome-wide and phase-specific DNA-binding rhythms of BMAL1 control circadian output functions in mouse liver
The mammalian circadian clock uses interlocked negative feedback loops in which the
heterodimeric basic helix-loop-helix transcription factor BMAL1/CLOCK is a master …
heterodimeric basic helix-loop-helix transcription factor BMAL1/CLOCK is a master …
Cellular clocks in AVP neurons of the SCN are critical for interneuronal coupling regulating circadian behavior rhythm
The suprachiasmatic nucleus (SCN), the primary circadian pacemaker in mammals, is a
network structure composed of multiple types of neurons. Here, we report that mice with a …
network structure composed of multiple types of neurons. Here, we report that mice with a …
Molecular components of the circadian clock in mammals
JS Takahashi - Diabetes, Obesity and Metabolism, 2015 - Wiley Online Library
The circadian clock mechanism in animals involves a transcriptional feedback loop in which
the bHLH‐PAS proteins CLOCK and BMAL1 form a transcriptional activator complex to …
the bHLH‐PAS proteins CLOCK and BMAL1 form a transcriptional activator complex to …
A diversity of paracrine signals sustains molecular circadian cycling in suprachiasmatic nucleus circuits
ES Maywood, JE Chesham… - Proceedings of the …, 2011 - National Acad Sciences
The suprachiasmatic nucleus (SCN) is the principal circadian pacemaker of mammals,
coordinating daily rhythms of behavior and metabolism. Circadian timekeeping in SCN …
coordinating daily rhythms of behavior and metabolism. Circadian timekeeping in SCN …
Neurobiology of food anticipatory circadian rhythms
RE Mistlberger - Physiology & behavior, 2011 - Elsevier
Mistlberger, RE Neurobiology of food anticipatory circadian rhythms. Physiol Behav 00 (00):
000–000, 2011. Circadian rhythms in mammals can be entrained by daily schedules of light …
000–000, 2011. Circadian rhythms in mammals can be entrained by daily schedules of light …