Mesenchymal stem cells (MSC s) have recently generated great interest in the fields of
regenerative medicine and immunotherapy due to their unique biologic properties. In this …

Mesenchymal stromal cell (MSC) metabolism plays a crucial role in the surrounding
microenvironment in both normal physiology and pathological conditions. While MSCs …

Stem cells have shown substantial promise for various diseases in preclinical and clinical
trials. However, low cell engraftment rates significantly limit the clinical translation of stem …

Mesenchymal stem cells (MSCs) are primary candidates in cell therapy and tissue
engineering and are being tested in clinical trials for a wide range of diseases. Originally …

Recent advances in understanding the cellular and molecular signaling pathways and
global transcriptional regulators of adult mesenchymal stem cells have provided new …

Mesenchymal stem cells (MSC) are adult multipotent cells found in bone marrow, adipose
tissue, and other adult tissues. MSC have been shown to improve regeneration of injured …

Changes in oxygen concentrations affect many of the innate characteristics of stem and
progenitor cells. Human mesenchymal stem cells (hMSCs) were maintained under hypoxic …

Human mesenchymal stem cells (MSCs) reside under hypoxic conditions in vivo, between
4% and 7% oxygen. Differentiation of MSCs under hypoxic conditions results in inhibited …

Mesenchymal stem cells (MSC) are capable of differentiating into bone, fat, cartilage, tendon
and other organ progenitor cells. Despite the abundance of MSC within the organism, little is …

In vitro hypoxic preconditioning (HP) of mesenchymal stem cells (MSCs) could ameliorate
their viability and tissue repair capabilities after transplantation into the injured tissue …