Nanoparticles (Nps) have revolutionized the landscape of many treatments, by modifying not
only pharmacokinetic properties of the encapsulated agent, but also providing a significant …

Cancer is a leading cause of death in many countries around the world. However, the
efficacy of current standard treatments for a variety of cancers is suboptimal. First, most …

Since their discovery in the 1960s, liposomes have been studied in depth, and they continue
to constitute a field of intense research. Liposomes are valued for their biological and …

Micelles as colloidal suspension have attracted considerable attention due to their potential
use for both cancer diagnosis and therapy. These structures have proven their ability to …

When nanoparticles (NPs) enter a physiological environment, medium components compete
for binding to the NP surface leading to formation of a rich protein shell known as the …

Vesicles are microscopic sacs that enclose a volume with a molecularly thin membrane. The
membranes are generally self-directed assemblies of amphiphilic molecules with a dual …

Gene therapy, as an emerging therapeutic approach, has shown remarkable advantages in
the treatment of some major diseases. With the deepening of genomics research, people …

Tumor specific drug delivery has become increasingly interesting in cancer therapy, as the
use of chemotherapeutics is often limited due to severe side effects. Conventional drug …

PEG-modified lipid vesicles have already shown considerable utility in delaying vesicle
clearance from the circulation. They are, however, limited in their ability to stably integrate …

pH-sensitive PEGylated (with PEG-PE) long-circulating liposomes (HSPC: cholesterol and
Doxil®), modified with cell-penetrating TAT peptide (TATp) moieties and cancer-specific …