Cationic polymers and their therapeutic potential

SK Samal, M Dash, S Van Vlierberghe… - Chemical Society …, 2012 - pubs.rsc.org
The last decade has witnessed enormous research focused on cationic polymers. Cationic
polymers are the subject of intense research as non-viral gene delivery systems, due to their …

Detection of daunomycin using phosphatidylserine and aptamer co-immobilized on Au nanoparticles deposited conducting polymer

P Chandra, HB Noh, MS Won, YB Shim - Biosensors and Bioelectronics, 2011 - Elsevier
A highly sensitive and selective sensor for daunomycin was developed using
phosphatidylserine (PS) and aptamer as bioreceptors. The PS and aptamer were co …

[HTML][HTML] Dendronized gold nanoparticles for siRNA delivery

ST Kim, A Chompoosor, YC Yeh, SS Agasti… - Small (Weinheim an …, 2012 - ncbi.nlm.nih.gov
Small interfering RNA (siRNA) is a versatile tool for regulation of gene expression.[1] The
ability of siRNA to silence translation and protein expression of cognate cellular mRNA …

Nucleic acids based polyelectrolyte complexes: Their complexation mechanism, morphology, and stability

YH Kim, K Lee, S Li - Chemistry of Materials, 2021 - ACS Publications
Nucleic acids are a special class of negatively charged polymers, and they can complex with
cationic small molecules and polymers to form polyelectrolyte complexes of rich …

Chitosan-based coacervate polymers for propolis encapsulation: release and cytotoxicity studies

T Sato, D Mello, L Vasconcellos, AJM Valente… - International journal of …, 2020 - mdpi.com
Chitosan-DNA (CS-DNA) and Chitosan-Pectin (CS-P) hydrogels were formulated as a
sustained drug delivery carrier for drug delivery. For this, hydrogels were prepared by …

Fluorescent nucleic acid systems for biosensors

A Podder, HJ Lee, BH Kim - Bulletin of the Chemical Society of …, 2021 - academic.oup.com
Modified nucleic acids have a wide range of applications in many areas of biochemistry. In
particular, fluorescence-based nucleic acid systems have been studied extensively for their …

Protonation-mediated DNA tile self-assembly with nuclease resistance characteristic for signal-amplified detection of microRNAs

Y Peng, D Li, B Qiao, Z Gao, Q Pu, H Pang, X Lai… - Biosensors and …, 2024 - Elsevier
DNA nanotechnology, developing rapidly in recent years, has unprecedented superiorities
in biological application-oriented research including high programmability, convenient …

Targeted siRNA delivery using lipid nanoparticles

A Jorge, A Pais, C Vitorino - Drug Delivery Systems, 2020 - Springer
Efficient intracellular delivery of small-interfering ribonucleic acid (siRNA) to the target organ
or tissues in the body is assumed as the main hurdle for a widespread use of siRNAs in the …

Solution conformation of polymer brushes determines their interactions with DNA and transfection efficiency

M Krishnamoorthy, D Li, AS Sharili… - …, 2017 - ACS Publications
Polymer brush-functionalized nanomaterials offer interesting features for the design of gene
delivery vectors as their physicochemical and structural properties can be designed …

Evaluation of chitosan-tripolyphosphate nanoparticles as a p-shRNA delivery vector: formulation, optimization and cellular uptake study

M Karimi, P Avci, M Ahi, T Gazori… - … and drug delivery, 2013 - ingentaconnect.com
Polysaccharides (especially chitosan) have recently attracted much attention as gene
therapy delivery vehicles for their unique properties such as biocompatibility …