The regulation and functions of DNA and RNA G-quadruplexes
DNA and RNA can adopt various secondary structures. Four-stranded G-quadruplex (G4)
structures form through self-recognition of guanines into stacked tetrads, and considerable …
structures form through self-recognition of guanines into stacked tetrads, and considerable …
Metal cations in G-quadruplex folding and stability
D Bhattacharyya, G Mirihana Arachchilage… - Frontiers in …, 2016 - frontiersin.org
This review is focused on the structural and physicochemical aspects of metal cation
coordination to G-Quadruplexes (GQ) and their effects on GQ stability and conformation. G …
coordination to G-Quadruplexes (GQ) and their effects on GQ stability and conformation. G …
RNA G-quadruplexes in biology: principles and molecular mechanisms
Abstract G-quadruplexes (G4s) are extremely stable DNA or RNA secondary structures
formed by sequences rich in guanine. These structures are implicated in many essential …
formed by sequences rich in guanine. These structures are implicated in many essential …
G-quadruplexes: prediction, characterization, and biological application
CK Kwok, CJ Merrick - Trends in biotechnology, 2017 - cell.com
Guanine (G)-rich sequences in nucleic acids can assemble into G-quadruplex structures that
involve G-quartets linked by loop nucleotides. The structural and topological diversity of G …
involve G-quartets linked by loop nucleotides. The structural and topological diversity of G …
RNA G-quadruplexes (rG4s): genomics and biological functions
Abstract G-quadruplexes (G4s) are non-classical DNA or RNA secondary structures that
have been first observed decades ago. Over the years, these four-stranded structural motifs …
have been first observed decades ago. Over the years, these four-stranded structural motifs …
Properties and biological impact of RNA G-quadruplexes: from order to turmoil and back
P Kharel, G Becker, V Tsvetkov… - Nucleic acids research, 2020 - academic.oup.com
Abstract Guanine-quadruplexes (G4s) are non-canonical four-stranded structures that can
be formed in guanine (G) rich nucleic acid sequences. A great number of G-rich sequences …
be formed in guanine (G) rich nucleic acid sequences. A great number of G-rich sequences …
rG4-seq reveals widespread formation of G-quadruplex structures in the human transcriptome
CK Kwok, G Marsico, AB Sahakyan, VS Chambers… - Nature …, 2016 - nature.com
We introduce RNA G-quadruplex sequencing (rG4-seq), a transcriptome-wide RNA G-
quadruplex (rG4) profiling method that couples rG4-mediated reverse transcriptase stalling …
quadruplex (rG4) profiling method that couples rG4-mediated reverse transcriptase stalling …
METTL1 promotes let-7 MicroRNA processing via m7G methylation
methylguanosine (m7G) is present at mRNA caps and at defined internal positions within
tRNAs and rRNAs. However, its detection within low-abundance mRNAs and microRNAs …
tRNAs and rRNAs. However, its detection within low-abundance mRNAs and microRNAs …
RNA G-quadruplexes: emerging mechanisms in disease
A Cammas, S Millevoi - Nucleic acids research, 2017 - academic.oup.com
Abstract RNA G-quadruplexes (G4s) are formed by G-rich RNA sequences in protein-coding
(mRNA) and non-coding (ncRNA) transcripts that fold into a four-stranded conformation …
(mRNA) and non-coding (ncRNA) transcripts that fold into a four-stranded conformation …
The diverse structural landscape of quadruplexes
G‐quadruplexes are secondary structures formed in G‐rich sequences in DNA and RNA.
Considerable research over the past three decades has led to in‐depth insight into these …
Considerable research over the past three decades has led to in‐depth insight into these …