Abstract Background Hepatitis C virus (HCV) exhibits great genetic diversity and is classified
into 7 genotypes (GTs), with varied geographic prevalence. Until the recent development of …

Abstract Background Hepatitis C virus (HCV) is currently classified into 8 genotypes and 86
subtypes. The objective of this study was to characterize novel HCV subtypes and to …

Background & Aims HCV genotype, subtype, and presence of resistance-associated
substitutions (RASs) are key determinants for the selection of direct-acting antiviral (DAA) …

The significance of the clinical impact of direct‐acting antiviral (DAA) resistance‐associated
substitutions (RASs) in hepatitis C virus (HCV) on treatment failure is unclear. No …

Background Limited treatment data are available for hepatitis C virus (HCV) in sub-Saharan
Africa, especially for genotype 4. Our objective was to establish the safety and efficacy of …

The routine availability of high-depth virus sequence data would allow the sensitive
detection of resistance-associated variants that can jeopardize HIV or hepatitis C virus …

Abstract Background Hepatitis C virus (HCV) is a rapidly evolving RNA virus that has been
classified into seven genotypes. All HCV genotypes cause chronic hepatitis, which ultimately …

While the prospect of viral cure is higher than ever for individuals infected with the hepatitis
C virus (HCV) due to ground-breaking progress in antiviral treatment, success rates are still …

Background Despite the high sustained virological response rates achieved with current
directly-acting antiviral agents (DAAs) against hepatitis C virus (HCV), around 5–10% of …

Hepatitis is a major public health issue, affecting 10–17 million people worldwide, with its
prevalence continuously increasing. The Hepatitis C virus (HCV) is responsible for liver …