microRNA functions
N Bushati, SM Cohen - Annu. Rev. Cell Dev. Biol., 2007 - annualreviews.org
microRNAs (miRNAs) are small noncoding RNAs that play important roles in
posttranscriptional gene regulation. In animal cells, miRNAs regulate their targets by …
posttranscriptional gene regulation. In animal cells, miRNAs regulate their targets by …
MicroRNA-206: the skeletal muscle-specific myomiR
JJ McCarthy - Biochimica et Biophysica Acta (BBA)-Gene Regulatory …, 2008 - Elsevier
MicroRNAs (miRNAs) are a class of non-coding RNAs involved in post-transcriptional gene
silencing. A small number of striated muscle-specific miRNAs have been identified and …
silencing. A small number of striated muscle-specific miRNAs have been identified and …
[HTML][HTML] A mammalian microRNA expression atlas based on small RNA library sequencing
MicroRNAs (miRNAs) are small noncoding regulatory RNAs that reduce stability and/or
translation of fully or partially sequence-complementary target mRNAs. In order to identify …
translation of fully or partially sequence-complementary target mRNAs. In order to identify …
miR-499 regulates mitochondrial dynamics by targeting calcineurin and dynamin-related protein-1
JX Wang, JQ Jiao, Q Li, B Long, K Wang, JP Liu… - Nature medicine, 2011 - nature.com
Myocardial infarction is a leading cause of mortality worldwide. Here we report that
modulation of microRNA-499 (miR-499) levels affects apoptosis and the severity of …
modulation of microRNA-499 (miR-499) levels affects apoptosis and the severity of …
The regulatory activity of microRNA* species has substantial influence on microRNA and 3′ UTR evolution
K Okamura, MD Phillips, DM Tyler, H Duan… - Nature structural & …, 2008 - nature.com
During microRNA (miRNA) biogenesis, one strand of a∼ 21–22-nucleotide RNA duplex is
preferentially selected for entry into a silencing complex. The other strand, known as the …
preferentially selected for entry into a silencing complex. The other strand, known as the …
MicroRNAs potentiate neural development
SK Fineberg, KS Kosik, BL Davidson - Neuron, 2009 - cell.com
MicroRNAs (miRNAs) are endogenously expressed noncoding RNAs that regulate mRNA
expression. In vertebrates, more distinct miRNAs are expressed in the brain than in any …
expression. In vertebrates, more distinct miRNAs are expressed in the brain than in any …
MicroRNAs show a wide diversity of expression profiles in the developing and mature central nervous system
M Kapsimali, WP Kloosterman, E de Bruijn, F Rosa… - Genome biology, 2007 - Springer
Background MicroRNA (miRNA) encoding genes are abundant in vertebrate genomes but
very few have been studied in any detail. Bioinformatic tools allow prediction of miRNA …
very few have been studied in any detail. Bioinformatic tools allow prediction of miRNA …
Chromatin crosstalk in development and disease: lessons from REST
L Ooi, IC Wood - Nature Reviews Genetics, 2007 - nature.com
Protein complexes that contain chromatin-modifying enzymes have an important role in
regulating gene expression. Recent studies have shown that a single transcription factor, the …
regulating gene expression. Recent studies have shown that a single transcription factor, the …
Inference of miRNA targets using evolutionary conservation and pathway analysis
Background MicroRNAs have emerged as important regulatory genes in a variety of cellular
processes and, in recent years, hundreds of such genes have been discovered in animals …
processes and, in recent years, hundreds of such genes have been discovered in animals …
A GATA-1-regulated microRNA locus essential for erythropoiesis
LC Dore, JD Amigo, CO Dos Santos… - Proceedings of the …, 2008 - National Acad Sciences
MicroRNAs (miRNAs) control tissue development, but their mechanism of regulation is not
well understood. We used a gene complementation strategy combined with microarray …
well understood. We used a gene complementation strategy combined with microarray …