Haloperidol‐induced catalepsy as an animal model for parkinsonism: A systematic review of experimental studies

I Waku, MS Magalhaes, CO Alves… - European Journal of …, 2021 - Wiley Online Library
Several useful animal models for parkinsonism have been developed so far. Haloperidol‐
induced catalepsy is often used as a rodent model for the study of motor impairments …

Rodent brain pathology, audiogenic epilepsy

IB Fedotova, NM Surina, GM Nikolaev, AV Revishchin… - Biomedicines, 2021 - mdpi.com
The review presents data which provides evidence for the internal relationship between the
stages of rodent audiogenic seizures and post-ictal catalepsy with the general pattern of …

Acute administration of dopaminergic drugs has differential effects on locomotion in larval zebrafish

TD Irons, PE Kelly, DL Hunter, RC Macphail… - Pharmacology …, 2013 - Elsevier
Altered dopaminergic signaling causes behavioral changes in mammals. In general,
dopaminergic receptor agonists increase locomotor activity, while antagonists decrease …

Local field potential (LFP) power and phase-amplitude coupling (PAC) changes in the striatum and motor cortex reflect neural mechanisms associated with …

C Reakkamnuan, E Kumarnsit, D Cheaha - Progress in Neuro …, 2023 - Elsevier
Impairments in motor control are the primary feature of Parkinson's disease, which is caused
by dopaminergic imbalance in the basal ganglia. Identification of neural biomarkers of …

Characteristics of basolateral amygdala neuronal firing on a spatial memory task involving differential reward.

WE Pratt, SJY Mizumori - Behavioral neuroscience, 1998 - psycnet.apa.org
Previous research has shown that spatial, movement, and reward information is integrated
within the ventral striatum (VS). The present study examined the possible contribution of the …

Paradoxical kinesia may no longer be a paradox waiting for 100 years to be unraveled

L Melo-Thomas, RKW Schwarting - Reviews in the Neurosciences, 2023 - degruyter.com
Parkinson's disease (PD) is a progressive neurodegenerative disorder mainly characterized
by bradykinesia and akinesia. Interestingly, these motor disabilities can depend on the …

Dopamine D2-Like Receptors Modulate Unconditioned Fear: Role of the Inferior Colliculus

AR de Oliveira, AC Colombo, S Muthuraju… - PLoS …, 2014 - journals.plos.org
Background A reduction of dopamine release or D2 receptor blockade in the terminal fields
of the mesolimbic system clearly reduces conditioned fear. Injections of haloperidol, a …

Dissociated neurons and glial cells derived from rat inferior colliculi after digestion with papain

O Kaiser, P Aliuos, K Wissel, T Lenarz, D Werner… - PLoS …, 2013 - journals.plos.org
The formation of gliosis around implant electrodes for deep brain stimulation impairs
electrode–tissue interaction. Unspecific growth of glial tissue around the electrodes can be …

Dopamine D2 receptors regulate unconditioned fear in deep layers of the superior colliculus and dorsal periaqueductal gray

S Muthuraju, T Talbot, ML Brandão - Behavioural Brain Research …, 2016 - Elsevier
Rationale Electrical and chemical stimulation of the dorsal periaqueductal gray (dPAG),
deep layers of the superior colliculus (dlSC), and inferior colliculus (IC) causes freezing and …

[HTML][HTML] Nanostarch based nanoencapsulation of Mucuna pruriens extract and its evaluation as anti-parkinsonian drug

RE Sardjono, R Gunawan, A Kadarohman… - Case Studies in …, 2024 - Elsevier
Parkinson's disease is a neurodegenerative disease caused by low dopamine levels in the
brain. This study aims to obtain the optimum condition for M. pruriens extract …