Targeting STAT3 signaling pathway in cancer by agents derived from Mother Nature

CD Mohan, S Rangappa, HD Preetham… - Seminars in cancer …, 2022 - Elsevier
Signal transducer and activator of transcription (STAT) proteins are latent transcription
factors that reside in the cytoplasm of several types of cells. In canonical signaling, upon …

Selected hepatoprotective herbal medicines: Evidence from ethnomedicinal applications, animal models, and possible mechanism of actions

M Ali, T Khan, K Fatima, QUA Ali, M Ovais… - Phytotherapy …, 2018 - Wiley Online Library
Insight into the hepatoprotective effects of medicinally important plants is important, both for
physicians and researchers. Main reasons for the use of herbal medicine include their lesser …

[HTML][HTML] In silico analyses of toxicity of the major constituents of essential oils from two Ipomoea L. species

OS da Silva Júnior, CJP Franco, AAB de Moraes… - Toxicon, 2021 - Elsevier
Convolvulaceae Juss. is a family of vines and shrubs composed of species of ecological and
economic importance. Ipomoea asarifolia (Desr.) Roem. & Schult. and I. setifera Poir. are …

Traditional Medicinal Uses, Phytochemistry, Biological Properties, and Health Applications of Vitex sp.

N Kamal, NS Mio Asni, INA Rozlan, MAH Mohd Azmi… - Plants, 2022 - mdpi.com
The genus Vitex is also known as a chaste tree, in which it is a large shrub native to the
tropical and subtropical regions of the world. A diverse range of species is distributed …

A Medicinal Halophyte Ipomoea pes-caprae (Linn.) R. Br.: A Review of Its Botany, Traditional Uses, Phytochemistry, and Bioactivity

G Akinniyi, J Lee, H Kim, JG Lee, I Yang - Marine Drugs, 2022 - mdpi.com
Ipomoea pes-caprae (Linn.) R. Br.(Convolvulaceae) is a halophytic plant that favorably
grows in tropical and subtropical countries in Asia, America, Africa, and Australia. Even …

An overview of the potential antineoplastic effects of casticin

S Ramchandani, I Naz, JH Lee, MR Khan, KS Ahn - Molecules, 2020 - mdpi.com
Cancer persists as one of the leading causes of deaths worldwide, contributing to
approximately 9.6 million deaths per annum in recent years. Despite the numerous …

[HTML][HTML] Topical gel containing phenolic-rich extract from Ipomoea pes-capre leaf (Convolvulaceae) has anti-inflammatory, wound healing, and antiophidic properties

JB Xavier-Santos, JGR Passos, JAS Gomes… - Biomedicine & …, 2022 - Elsevier
The growing use of phytotherapy in clinical practice arouses interest in studies using
medicinal plants as active ingredients for new medicines. Ipomoea pes-caprae has a wide …

Casticin from Vitex species: a short review on its anticancer and anti-inflammatory properties

EWC Chan, SK Wong, HT Chan - Journal of integrative medicine, 2018 - Elsevier
This short review provides an update of the anticancer and anti-inflammatory properties of
casticin from Vitex species. Casticin is a polymethylflavone with three rings, an orthocatechol …

Medicinal uses, pharmacology, and phytochemistry of Convolvulaceae plants with central nervous system efficacies: A systematic review

GT Chen, Y Lu, M Yang, JL Li… - Phytotherapy Research, 2018 - Wiley Online Library
Central nervous system (CNS) disorders play a major impact on individual lives and place a
severe strain on health care resources. Convolvulaceae is a family comprising …

Effects of Vitex trifolia L. leaf extracts and phytoconstituents on cytokine production in human U937 macrophages

HN Wee, SY Neo, D Singh, HC Yew, ZY Qiu… - … medicine and therapies, 2020 - Springer
Background Dysregulation of pro-inflammatory cytokines such as tumor necrosis factor-α
(TNF-α) and interleukin-1β (IL-1β) form the basis of immune-mediated inflammatory …