Astrocytes are key homeostatic regulators in the central nervous system and play important
roles in physiology. After brain damage caused by eg, status epilepticus, traumatic brain …

Connexins are ubiquitous channel forming proteins that assemble as plasma membrane
hemichannels and as intercellular gap junction channels that directly connect cells. In the …

CB1 and CB2 receptors are activated by a plethora of cannabinoid compounds, be they
endogenously‐produced, plant‐derived or synthetic. These receptors are expressed by …

Glial cells are emerging from the background to become more prominent in our thinking
about integration in the nervous system. Given that glial cells associated with synapses …

The medicinal properties of marijuana have been recognized for centuries, but clinical and
societal acceptance of this drug of abuse as a potential therapeutic agent remains fiercely …

Cannabinoids have a long history of consumption for recreational and medical reasons. The
primary active constituent of the hemp plant Cannabis sativa is Δ9-tetrahydrocannabinol (Δ9 …

▪ Abstract Many neurons in the mammalian central nervous system communicate through
electrical synapses, defined here as gap junction–mediated connections. Electrical …

The existence of an endogenous cannabinoid system was demonstrated conclusively with
the discovery of endogenous brain constituents capable of activating the cannabinoid …

Adjacent cells share ions, second messengers and small metabotes through intercellular
channels which are present in gap junctions. This type of intercellular communication …

Calcium waves represent a widespread form of intercellular communication. Although they
have been thought for a long time to require gap junctions, we recently demonstrated that …