Synthesis and functionalization of hyperbranched polymers for targeted drug delivery

A Kavand, N Anton, T Vandamme, CA Serra… - Journal of Controlled …, 2020 - Elsevier
Hyperbranched polymers (HBPs) have found use in a wide range of applications, such as
optical, electronic and magnetic materials, coatings, additives, supramolecular chemistry …

Smart redox-sensitive micelles based on chitosan for dasatinib delivery in suppressing inflammatory diseases

H Vakilzadeh, J Varshosaz, M Dinari, M Mirian… - International Journal of …, 2023 - Elsevier
Dasatinib (DAS) exhibits anti-inflammatory effects by retrieving the balance between
inflammatory and anti-inflammatory cytokines secreted by macrophages. The aim of this …

A novel cytostatic form of autophagy in sensitization of non-small cell lung cancer cells to radiation by vitamin D and the vitamin D analog, EB 1089

K Sharma, RW Goehe, X Di, MA Hicks, SV Torti… - Autophagy, 2014 - Taylor & Francis
The standard of care for unresectable lung cancer is chemoradiation. However, therapeutic
options are limited and patients are rarely cured. We have previously shown that vitamin D …

The potential of pH-responsive PEG-hyperbranched polyacylhydrazone micelles for cancer therapy

J Yu, H Deng, F Xie, W Chen, B Zhu, Q Xu - Biomaterials, 2014 - Elsevier
Abstract pH-responsive hyperbranched polymers have attracted much attention due to their
unique properties for tumor-targeted drug delivery. In this study, we describe a pH …

Ionic Ring-Opening Polymerization for the Synthesis of Star-Shaped Polymers

AN Blokhin, MM Dudkina, AV Tenkovtsev - Polymer Science, Series C, 2022 - Springer
Features of ionic ring-opening polymerization for preparing star-shaped polymers are
considered. The possibilities of controlled synthesis of star-shaped structures using cyclic …

Poly-(3-ethyl-3-hydroxymethyl) oxetanes—synthesis and adhesive interactions with polar substrates

P Parzuchowski, MŁ Mamiński - Polymers, 2020 - mdpi.com
Hyperbranched polyoxetanes are a relatively new class of polymers. These are branched
polyethers that are synthesized from oxetanes—four-member cyclic ethers bearing …

Co‐delivery of methotrexate and doxorubicin via nanocarriers of star‐like poly(DMAEMA‐block‐HEMA‐block‐AAc) terpolymers

M Saraei, R Sarvari, B Massoumi… - Polymer …, 2019 - Wiley Online Library
Combined therapy is a promising strategy for clinical cancer treatment with synergistic
effects. The purpose of the work reported was to evaluate a smart nanocarrier for co‐delivery …

A dual pH/Redox responsive copper-ligand nanoliposome bioactive complex for the treatment of chronic inflammation

S Mavuso, YE Choonara, T Marimuthu, P Kumar… - International journal of …, 2016 - Elsevier
A novel dual pH/redox-responsive polymeric nanoliposome system (NLs) loaded with a
copper-liganded bioactive complex was prepared and designed as a controlled delivery …

Synthesis and characterization of clickable cytocompatible poly (ethylene glycol)-grafted polyoxetane brush polymers

OY Zolotarskaya, Q Yuan, KJ Wynne, H Yang - Macromolecules, 2013 - ACS Publications
We report a new family of clickable poly (ethylene glycol)(PEG)-grafted polyoxetane brush
polymers as a potential modular platform for delivery of drugs and imaging agents. 3-Ethyl-3 …

Cationic copolymerization of 3, 3-bis (hydroxymethyl) oxetane and glycidol: biocompatible hyperbranched polyether polyols with high content of primary hydroxyl …

EM Christ, D Hobernik, M Bros, M Wagner… - …, 2015 - ACS Publications
The cationic ring-opening copolymerization of 3, 3-bis (hydroxymethyl) oxetane (BHMO) with
glycidol using different comonomer ratios (BHMO content from 25 to 90%) and BF3OEt2 as …