Cannabinoids modulate the microbiota–gut–brain axis in HIV/SIV infection by reducing neuroinflammation and dysbiosis while concurrently elevating …

M McDew-White, E Lee, LS Premadasa… - Journal of …, 2023 - Springer
Background Although the advent of combination anti-retroviral therapy (cART) has
transformed HIV into a manageable chronic disease, an estimated 30–50% of people living …

Molecular Role of HIV-1 Human Receptors (CCL5–CCR5 Axis) in neuroAIDS: A Systematic Review

MJA Silva, RL Marinho, YC Rodrigues, TP Brasil… - Microorganisms, 2024 - mdpi.com
Chronic HIV-1 infection can cause neurological illness, also known as HIV-associated
neurocognitive disorders (HAND). The elevated level of pro-inflammatory cytokines and …

Multimodal Approach to Neurocognitive Function in People Living with HIV in the cART Era: A Comprehensive Review

CD Moschopoulos, E Stanitsa, K Protopapas… - Life, 2024 - mdpi.com
Combination antiretroviral treatment (cART) has revolutionized the management of human
immunodeficiency virus (HIV) and has markedly improved the disease burden and life …

[HTML][HTML] CXCL13 neutralization attenuates neuropsychiatric manifestations in lupus-prone mice

MW Huang, AD Stock, C Putterman - Frontiers in Immunology, 2021 - frontiersin.org
Neuropsychiatric lupus (NPSLE), the nervous system presentation of systemic lupus
erythematosus (SLE), remains challenging to treat due to its unclear pathogenesis and lack …

Higher cerebrospinal fluid soluble urokinase-type plasminogen activator receptor, but not interferon γ-inducible protein 10, correlate with higher working memory …

SM De Almeida, I Rotta, B Tang, A Umlauf… - JAIDS Journal of …, 2022 - journals.lww.com
Background: We hypothesized that the induction of monocyte activation biomarkers,
especially soluble urokinase-type plasminogen activator receptor (suPAR) and interferon γ …

[HTML][HTML] Sustained type I interferon signaling after human immunodeficiency virus type 1 infection of human iPSC derived microglia and cerebral organoids

AJ Boreland, AC Stillitano, HC Lin, Y Abbo, RP Hart… - Iscience, 2024 - cell.com
Human immunodeficiency virus type-1 (HIV-1)-associated neurocognitive disorder (HAND)
affects up to half of people living with HIV-1 and causes long term neurological …

[HTML][HTML] Dysregulated neuroimmune interactions and sustained type I interferon signaling after human immunodeficiency virus type 1 infection of human iPSC derived …

AJ Boreland, AC Stillitano, HC Lin, Y Abbo, RP Hart… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Human immunodeficiency virus type-1 (HIV-1) associated neurocognitive disorder (HAND)
affects up to half of HIV-1 positive patients with long term neurological consequences …

HIV-1 subtype C Vpr amino acid residue 45Y and specific conserved fragments are associated with neurocognitive impairment and markers of viral load

V Ruhanya, GB Jacobs, RH Paul, JA Joska… - AIDS Research and …, 2023 - liebertpub.com
There is increasing evidence that HIV-1 viral protein R (Vpr) plays an important role in the
pathogenesis of cognitive impairment. We investigated the relationship between HIV-1 …

Soluble CD14 is subtype-dependent in serum but not in cerebrospinal fluid in people with HIV

SM de Almeida, B Tang, F Vaida, S Letendre… - Journal of …, 2022 - Elsevier
Monocytes and macrophages activation are crucial in human immunodeficiency virus (HIV)
central nervous system (CNS) infection and HIV associated neurocognitive disorders …

血清pro-BDNF, α-syn, RANTES 水平在不同HY 分期帕金森病患者中的变化及与认知功能障碍的关系.

周弋人, 缪礁丹, 杨一帆, 沈富伟… - Progress in Modern …, 2022 - search.ebscohost.com
摘要目的: 探讨血清脑源性神经营养因子前体蛋白(pro-BDNF), 琢-突触核蛋白(琢-syn), 活化T
细胞趋化因子(RANTES) 水平在不同Hoehn-Yahr (HY) 分期帕金森病(PD) …