Membrane homeostasis beyond fluidity: control of membrane compressibility

MF Renne, R Ernst - Trends in Biochemical Sciences, 2023 - cell.com
Biomembranes are complex materials composed of lipids and proteins that
compartmentalize biochemistry. They are actively remodeled in response to physical and …

The membrane surface as a platform that organizes cellular and biochemical processes

TA Leonard, M Loose, S Martens - Developmental cell, 2023 - cell.com
Membranes are essential for life. They act as semi-permeable boundaries that define cells
and organelles. In addition, their surfaces actively participate in biochemical reaction …

Oligomeric organization of membrane proteins from native membranes at nanoscale spatial and single-molecule resolution

G Walker, C Brown, X Ge, S Kumar… - Nature …, 2024 - nature.com
The oligomeric organization of membrane proteins in native cell membranes is a critical
regulator of their function. High-resolution quantitative measurements of oligomeric …

Optically Pure Double-Stranded Dinuclear Ir (III) Metallohelices Enabled Chirality-Induced Photodynamic Responses

X Li, Z Wang, X Hao, J Zhang, X Zhao… - Journal of the …, 2023 - ACS Publications
Investigation on the interactions between enantiomers of chiral drugs and biomolecules can
help precisely understand their biological behaviors in vivo and provide insights into the …

Cryo-EM architecture of a near-native stretch-sensitive membrane microdomain

JM Kefauver, M Hakala, L Zou, J Alba, J Espadas… - Nature, 2024 - nature.com
Biological membranes are partitioned into functional zones termed membrane
microdomains, which contain specific lipids and proteins,–. The composition and …

Tunable multivalent aptamer-based DNA nanostructures to regulate multiheteroreceptor-mediated tumor recognition

X Hu, H Chi, X Fu, J Chen, L Dong… - Journal of the …, 2024 - ACS Publications
Precise mapping and regulation of cell surface receptors hold immense significance in
disease treatment, such as cancer, infection, and neurodisorders, but also face enormous …

Lipids shape brain function through ion channel and receptor modulations: physiological mechanisms and clinical perspectives

S Incontro, ML Musella, M Sammari… - Physiological …, 2025 - journals.physiology.org
Lipids represent the most abundant molecular type in the brain, with a fat content of∼ 60%
of the dry brain weight in humans. Despite this fact, little attention has been paid to …

LPCAT1-mediated membrane phospholipid remodelling promotes ferroptosis evasion and tumour growth

Z Li, Y Hu, H Zheng, M Li, Y Liu, R Feng, X Li… - Nature cell …, 2024 - nature.com
The mechanisms underlying the dynamic remodelling of cellular membrane phospholipids
to prevent phospholipid peroxidation-induced membrane damage and evade ferroptosis, a …

Lipid sorting and organelle identity

Y Kim, CG Burd - Cold Spring Harbor Perspectives in …, 2023 - cshperspectives.cshlp.org
The sorting and trafficking of lipids between organelles gives rise to a dichotomy of bulk
membrane properties between organelles of the secretory and endolysosome networks …

[PDF][PDF] Recent advances in membrane mimetics for membrane protein research

JW Young - Biochemical Society Transactions, 2023 - portlandpress.com
Membrane proteins are a highly relevant class of biological molecules and comprise∼ 60%
of current drug targets. Before being analyzed by structural, biochemical, and biophysical …