Deintensification of treatment for human papillomavirus-related oropharyngeal cancer: Current state and future directions
EO Bigelow, TY Seiwert, C Fakhry - Oral oncology, 2020 - Elsevier
Human papillomavirus (HPV)-related oropharyngeal squamous cell cancer (OPSCC) has
emerged as a distinct clinical entity of head and neck cancer with expected high survival …
emerged as a distinct clinical entity of head and neck cancer with expected high survival …
Global prevalence of human papillomavirus-driven oropharyngeal squamous cell carcinoma following the ASCO guidelines: A systematic review and meta-analysis
BALA Mariz, LP Kowalski, WN William Jr… - Critical reviews in …, 2020 - Elsevier
Objectives to provide accurate information about the global prevalence of human
papillomavirus (HPV) in oropharyngeal squamous cell carcinomas (OPSCC). Material and …
papillomavirus (HPV) in oropharyngeal squamous cell carcinomas (OPSCC). Material and …
Association of pack-years of cigarette smoking with survival and tumor progression among patients treated with chemoradiation for head and neck cancer
Importance After 10 pack-years of smoking was initially established as a threshold for risk
stratification, subsequent clinical trials incorporated it to identify candidates for treatment …
stratification, subsequent clinical trials incorporated it to identify candidates for treatment …
The association of smoking and outcomes in HPV-positive oropharyngeal cancer: a systematic review
SY Chen, S Massa, AL Mazul, D Kallogjeri… - American Journal of …, 2020 - Elsevier
Purpose While smoking is linked to worse outcomes for human papillomavirus (HPV)-
related oropharyngeal squamous cell cancer (OPSCC), the magnitude of this association …
related oropharyngeal squamous cell cancer (OPSCC), the magnitude of this association …
Transitions in oral and gut microbiome of HPV+ oropharyngeal squamous cell carcinoma following definitive chemoradiotherapy (ROMA LA-OPSCC study)
M Oliva, PHH Schneeberger, V Rey, M Cho… - British journal of …, 2021 - nature.com
Background Oral and gut microbiomes have emerged as potential biomarkers in cancer. We
characterised the oral and gut microbiomes in a prospective observational cohort of HPV+ …
characterised the oral and gut microbiomes in a prospective observational cohort of HPV+ …
An infection-based murine model for papillomavirus-associated head and neck cancer
T Wei, D Buehler, E Ward-Shaw, PF Lambert - MBio, 2020 - Am Soc Microbiol
Human papillomavirus (HPV) is the most common sexually transmitted pathogen, and high-
risk HPVs contribute to 5% of human cancers, including 25% of head and neck squamous …
risk HPVs contribute to 5% of human cancers, including 25% of head and neck squamous …
Age-independent increasing prevalence of Human Papillomavirus-driven oropharyngeal carcinomas in North-East Italy
A Del Mistro, H Frayle, A Menegaldo, N Favaretto… - Scientific reports, 2020 - nature.com
HPV-driven oropharyngeal carcinomas (OPCs) show geographical variations with
increasing temporal trends in several areas. We investigated their frequency and clinical …
increasing temporal trends in several areas. We investigated their frequency and clinical …
Point/counterpoint: do we de-escalate treatment of HPV-associated oropharynx cancer now? And how?
LJ Wirth, B Burtness, CAO Nathan… - American Society of …, 2019 - ascopubs.org
HPV-positive (HPV+) oropharyngeal carcinoma (OPC) continues to increase in incidence
across the globe. Multimodality treatment offers a high likelihood of cure in HPV+ OPC but …
across the globe. Multimodality treatment offers a high likelihood of cure in HPV+ OPC but …
Evaluating the impact of smoking on disease‐specific survival outcomes in patients with human papillomavirus–associated oropharyngeal cancer treated with …
DF Roden, K Hobelmann, S Vimawala, T Richa… - Cancer, 2020 - Wiley Online Library
Background When treated nonsurgically with definitive chemoradiation, smokers with
human papillomavirus (HPV)–positive oropharyngeal squamous cell carcinoma (OPSCC) …
human papillomavirus (HPV)–positive oropharyngeal squamous cell carcinoma (OPSCC) …
Impact of Smoking on the Survival of Patients With High-risk HPV-positive HNSCC: A Meta-analysis
M Alotaibi, V Valova, T HÄnsel, C Stromberger, G Kofla… - in vivo, 2021 - iv.iiarjournals.org
Background/Aim: High risk Human papillomavirus (hr-HPV) and smoking are independant
risk factors for head and neck squamous cell carcinomas (HNSCC). While hr-HPV+ HNSCC …
risk factors for head and neck squamous cell carcinomas (HNSCC). While hr-HPV+ HNSCC …