Innate immunity of neonates and infants
JC Yu, H Khodadadi, A Malik, B Davidson… - Frontiers in …, 2018 - frontiersin.org
Many important events occur at birth. The fetus is suddenly removed from a protected intra-
uterine environment that is aquatic, warm, and nearly sterile, to the dry, cold external world …
uterine environment that is aquatic, warm, and nearly sterile, to the dry, cold external world …
NK cell recognition
LL Lanier - Annu. Rev. Immunol., 2005 - annualreviews.org
NK CELL RECOGNITION | Annual Reviews Menu Publications AZ Journal Information About
Subscribe Give Personal Register/Sign-in 0 Cart Help Journal Information Author Resource …
Subscribe Give Personal Register/Sign-in 0 Cart Help Journal Information Author Resource …
[HTML][HTML] The transcription factors T-bet and Eomes control key checkpoints of natural killer cell maturation
Natural killer (NK) cells play critical roles defending against tumors and pathogens. We
show that mice lacking both transcription factors Eomesodermin (Eomes) and T-bet failed to …
show that mice lacking both transcription factors Eomesodermin (Eomes) and T-bet failed to …
Self-tolerance of natural killer cells
Natural killer (NK) cells, similar to other lymphocytes, acquire tolerance to self. This means
that NK cells have the potential to attack normal self cells but that there are mechanisms to …
that NK cells have the potential to attack normal self cells but that there are mechanisms to …
A subset of natural killer cells achieves self-tolerance without expressing inhibitory receptors specific for self-MHC molecules
It is widely believed that self-tolerance of natural killer (NK) cells occurs because each NK
cell expresses at least one inhibitory receptor specific for a host major histocompatibility …
cell expresses at least one inhibitory receptor specific for a host major histocompatibility …
Regulation of the natural killer cell receptor repertoire
Natural killer cells express inhibitory receptors specific for MHC class I proteins and
stimulatory receptors with diverse specificities. The MHC-specific receptors discriminate …
stimulatory receptors with diverse specificities. The MHC-specific receptors discriminate …
Transcription from the RAG1 locus marks the earliest lymphocyte progenitors in bone marrow
H Igarashi, SC Gregory, T Yokota, N Sakaguchi… - Immunity, 2002 - cell.com
Abstract Viable Lin− CD27+ c-kit Hi Sca-1 Hi GFP+ cells recovered from heterozygous
RAG1/GFP knockin mice progressed through previously defined stages of B, T, and NK cell …
RAG1/GFP knockin mice progressed through previously defined stages of B, T, and NK cell …
Complex controls: the role of alternative promoters in mammalian genomes
JR Landry, DL Mager, BT Wilhelm - TRENDS in Genetics, 2003 - cell.com
Despite the wealth of sequence data available from human, mouse and other genomes, our
understanding of the mechanisms involved in regulating transcription and creating protein …
understanding of the mechanisms involved in regulating transcription and creating protein …
MHC class I–specific inhibitory receptors and their ligands structure diverse human NK-cell repertoires toward a balance of missing self-response
M Yawata, N Yawata, M Draghi… - Blood, The Journal …, 2008 - ashpublications.org
Variegated expression of 6 inhibitory HLA class I–specific receptors on primary NK cells was
studied using high-dimension flow cytometry in 58 humans to understand the structure and …
studied using high-dimension flow cytometry in 58 humans to understand the structure and …
The strength of inhibitory input during education quantitatively tunes the functional responsiveness of individual natural killer cells
P Brodin, T Lakshmikanth, S Johansson… - Blood, The Journal …, 2009 - ashpublications.org
Natural killer (NK) cells express inhibitory receptors for major histocompatibility complex
(MHC) class I. If self-MHC is down-regulated or absent, lack of inhibition triggers “missing …
(MHC) class I. If self-MHC is down-regulated or absent, lack of inhibition triggers “missing …