Decades of research have disclosed a plethora of alterations in protein glycosylation that
decisively impact in all stages of disease and ultimately contribute to more aggressive cell …

Altered metabolism and deregulated cellular energetics are now considered a hallmark of
all cancers. Glucose, glutamine, fatty acids, and amino acids are the primary drivers of tumor …

Many proteins in living organisms are glycosylated. As their glycan patterns exhibit protein‐,
cell‐, and tissue‐specific heterogeneity, changes in the glycosylation levels could serve as …

The Golgi-sialyltransferase ST6Gal1 (βgalactosidase α2, 6 sialyltransferase 1), adds the
negatively charged sugar, sialic acid, to the terminal galactose of N-glycosylated proteins …

Rationale: Epithelial-mesenchymal transition (EMT) has been recognized as an important
step toward high invasion and metastasis of many cancers including hepatocellular …

Simple Summary Cancer is a difficult-to-cure disease with high worldwide incidence and
mortality. Among the many changes observed in cancer cells and patient samples is altered …

The term “cancer” refers to a group of diseases involving abnormal cell growth with the
potential to invade or spread to other parts of the body. Epithelial–mesenchymal transition …

This review is the eighth update of the original article published in 1999 on the application of
Matrix‐assisted laser desorption/ionization mass spectrometry (MALDI) mass spectrometry …

Aberrant expression of glycans, ie, oligosaccharide moiety covalently attached to proteins or
lipids, is characteristic of various cancers, including urothelial ones. The binding of lectins to …

Bladder cancer (BC) is the 10th most common malignancy worldwide, with an estimated
573,000 new cases and 213,000 deaths in 2020. Available therapeutic approaches are still …