Hypertension is a prevalent health problem inducing many organ damages. The
pathogenesis of hypertension involves a complex integration of different organ systems …

Inappropriate therapy of postoperative pain in laparoscopic cholecystectomy may lead to
late mobilization, patient dissatisfaction, delayed hospital discharge, and chronic pain …

Background: Kv7 neuronal channels are recognized as a potential drug target for anxiolytic
effects. We hypothesize that flupirtine as a potassium channel opener would effectively …

Background Effective control of pain postoperatively is essential in providing enhanced
patient care and a cost-effective hospital stay. Though many treatment modalities exist for …

Methods: PubMed, Embase and the Cochrane Central Register of Controlled Trials
(CENTRAL) were explored for the randomised controlled trials (RCTs) which compared …

Боль в спине (дорсалгия) беспокоит в разные периоды жизни подавляющее
большинство людей, занимая по распространенности 2-е место после простудных …

Fibromyalgia is a complex disorder characterised by chronic pain, fatigue, sleep disturbance
and cognitive dysfunction with limited benefit gained with current therapies. The mean …

Лапароскопическая холецистэктомия (ЛХЭ) является золотым стандартом
хирургического лечения больных калькулезным холециститом. Сложилось …

Laparoscopic cholecystectomy is the «gold» standard for the surgical treatment of patients
with calculous cholecystitis. It is believed that laparoscopic cholecystectomy is not only safe …

Background: Functional endoscopic sinus surgery (FESS) is the mainstay therapeutic
management for nasal pathologies. We evaluated flupirtine, a centrally acting analgesic, for …