Single nucleus multiomics identifies ZEB1 and MAFB as candidate regulators of Alzheimer's disease-specific cis-regulatory elements
AG Anderson, BB Rogers, JM Loupe… - Cell Genomics, 2023 - cell.com
Cell type-specific transcriptional differences between brain tissues from donors with
Alzheimer's disease (AD) and unaffected controls have been well documented, but few …
Alzheimer's disease (AD) and unaffected controls have been well documented, but few …
UBE3A: Bridging the gap between neurodevelopment, neural function, and neurodegenerative woes
KR Nash, UK Jinwal, KM Bhat - Journal of Alzheimer's …, 2024 - journals.sagepub.com
Post-translational modifications (PTMs) of proteins play a significant role in normal protein
function but can also be instrumental in disease pathogenesis. One critical yet under-studied …
function but can also be instrumental in disease pathogenesis. One critical yet under-studied …
Using GWAS summary data to impute traits for genotyped individuals
Genome-wide association study (GWAS) summary data have become extremely useful in
daily routine data analysis, largely facilitating new methods development and new …
daily routine data analysis, largely facilitating new methods development and new …