Non-invasive diagnosis and monitoring of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis

MA Tincopa, R Loomba - The Lancet Gastroenterology & Hepatology, 2023 - thelancet.com
Non-alcoholic fatty liver disease (NAFLD) is a highly prevalent form of chronic liver disease
that poses challenges in diagnosis and risk stratification. Non-alcoholic steatohepatitis …

Risk stratification and early detection biomarkers for precision HCC screening

YT Lee, N Fujiwara, JD Yang, Y Hoshida - Hepatology, 2023 - journals.lww.com
Hepatocellular carcinoma (HCC) mortality remains high primarily due to late diagnosis as a
consequence of failed early detection. Professional societies recommend semi‐annual HCC …

AASLD Practice Guidance on the clinical assessment and management of nonalcoholic fatty liver disease

ME Rinella, BA Neuschwander-Tetri, MS Siddiqui… - Hepatology, 2023 - journals.lww.com
Abbreviations: AASLD, American Association for the Study of Liver Diseases; AI, artificial
intelligence; ALT, alanine aminotransferase; AST, aspartate aminotransferase; AUROC …

Diagnostic accuracy of FibroScan-AST (FAST) score for the non-invasive identification of patients with fibrotic non-alcoholic steatohepatitis: a systematic review and …

F Ravaioli, E Dajti, A Mantovani, PN Newsome… - Gut, 2023 - gut.bmj.com
Objective A simple combined score with liver stiffness, controlled attenuation parameter and
serum aspartate aminotransferase (AST), the FibroScan-AST (FAST) score, has been …

[HTML][HTML] Non-alcoholic fatty liver disease: Immunological mechanisms and current treatments

L Petagine, MG Zariwala, VB Patel - World Journal of …, 2023 - ncbi.nlm.nih.gov
Non-alcoholic fatty liver disease (NAFLD) causes significant global disease burden and is a
leading cause of mortality. NAFLD induces a myriad of aberrant changes in hepatocytes at …

New and emerging treatments for metabolic dysfunction-associated steatohepatitis

MA Tincopa, QM Anstee, R Loomba - Cell metabolism, 2024 - cell.com
Metabolic dysfunction-associated steatohepatitis (MASH) is a leading etiology of chronic
liver disease worldwide, with increasing incidence and prevalence in the setting of the …

[HTML][HTML] Non-invasive biomarkers for liver inflammation in non-alcoholic fatty liver disease: present and future

TCF Yip, F Lyu, H Lin, G Li, PC Yuen… - Clinical and …, 2023 - ncbi.nlm.nih.gov
Inflammation is the key driver of liver fibrosis progression in non-alcoholic fatty liver disease
(NAFLD). Unfortunately, it is often challenging to assess inflammation in NAFLD due to its …

How to Identify Advanced Fibrosis in Adult Patients with Non-Alcoholic Fatty Liver Disease (NAFLD) and Non-Alcoholic Steatohepatitis (NASH) Using Ultrasound …

MG Taru, L Neamti, V Taru, LM Procopciuc, B Procopet… - Diagnostics, 2023 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD), and its progressive form, non-alcoholic
steatohepatitis (NASH), represent, nowadays, real challenges for the healthcare system …

Cardiovascular and mortality outcomes with GLP-1 receptor agonists vs other glucose-lowering drugs in individuals with NAFLD and type 2 diabetes: a large …

A Krishnan, CV Schneider, Y Hadi, D Mukherjee… - Diabetologia, 2024 - Springer
Aims/hypothesis We aimed to determine whether the use of glucagon-like peptide-1
receptor agonists (GLP-1RA) in individuals with non-alcoholic fatty liver disease (NAFLD) …

Nonalcoholic fatty liver disease from a primary care perspective

JM Clark, DRH Cryer, M Morton… - Diabetes, Obesity and …, 2023 - Wiley Online Library
Nonalcoholic fatty liver disease (NAFLD) affects up to one‐third of the US population.
Approximately one‐fifth of patients with NAFLD have nonalcoholic steatohepatitis (NASH) …