Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive cancers,
associated with poor survival outcomes. Lack of early diagnosis, resistance to conventional …

Abstract Tumor-associated macrophages (TAMs), as a major and essential component of
tumor microenvironment (TME), play a critical role in orchestrating pancreatic cancer (PaC) …

Despite advancements in chemotherapy, the issue of resistance and non-responsiveness to
many chemotherapeutic drugs that are currently in clinical use still remains. Recently …

Pancreatic cancer, characterized by its poor prognosis, exhibits a marked resistance to
conventional chemotherapy and immunotherapy, underscoring the urgent need for more …

Pancreatic ductal adenocarcinoma (PDAC), a highly malignant neoplasm, is classified as
one of the most severe and devastating types of cancer. PDAC is a notable malignancy that …

Triple negative breast cancer (TNBC) subtype is characterized with higher EMT/stemness
properties and immune suppressive tumor microenvironment (TME). Women with advanced …

Research into cancer treatment has been mainly focused on developing therapies to directly
target cancer cells. Over the past decade, extensive studies have revealed critical roles of …

Triptolide (TPL) is a compound sourced from Tripterygium wilfordii Hook. F., a traditional
Chinese medicinal herb recognized for its impressive anti-inflammatory, anti-angiogenic …

Triptolide, a compound isolated from a Chinese medicinal herb, has potent antitumor,
immunosuppressive, and anti-inflammatory properties. Due to its interesting structural …

Cancer remains one of the greatest global health concerns. This is especially true for
gynecological cancers, which include cervical, ovarian, and endometrial cancers, and breast …