The impact of the Fungus-Host-Microbiota interplay upon Candida albicans infections: current knowledge and new perspectives

C d'Enfert, AK Kaune, LR Alaban… - FEMS microbiology …, 2021 - academic.oup.com
Candida albicans is a major fungal pathogen of humans. It exists as a commensal in the oral
cavity, gut or genital tract of most individuals, constrained by the local microbiota, epithelial …

Crossing kingdoms: how the mycobiota and fungal-bacterial interactions impact host health and disease

W Santus, JR Devlin, J Behnsen - Infection and Immunity, 2021 - Am Soc Microbiol
The term “microbiota” invokes images of mucosal surfaces densely populated with bacteria.
These surfaces and the luminal compartments they form indeed predominantly harbor …

Selection of cross-reactive T cells by commensal and food-derived yeasts drives cytotoxic TH1 cell responses in Crohn's disease

GR Martini, E Tikhonova, E Rosati, MB DeCelie… - Nature medicine, 2023 - nature.com
Aberrant CD4+ T cell reactivity against intestinal microorganisms is considered to drive
mucosal inflammation in inflammatory bowel diseases. The disease-relevant microbial …

The virota and its transkingdom interactions in the healthy infant gut

L Beller, W Deboutte, S Vieira-Silva… - Proceedings of the …, 2022 - National Acad Sciences
Virome and 16/18S analyses were performed on 304 longitudinal fecal samples of eight
infants. The gut virota—the collection of all viruses present in the gut—was dominated by …

The human mycobiome: colonization, composition and the role in health and disease

P Belvoncikova, P Splichalova, P Videnska, R Gardlik - Journal of Fungi, 2022 - mdpi.com
The mycobiome is the fungal component of the human microbial ecosystem that represents
only a small part of this environment but plays an essential role in maintaining homeostasis …

The role of gut mycobiome in health and diseases

L Zhang, H Zhan, W Xu, S Yan… - Therapeutic advances in …, 2021 - journals.sagepub.com
The gut microbiome comprised of microbes from multiple kingdoms, including bacteria,
fungi, and viruses. Emerging evidence suggests that the intestinal fungi (the gut …

Commensal fungi in intestinal health and disease

KS Ost, JL Round - Nature Reviews Gastroenterology & Hepatology, 2023 - nature.com
The microbiota is known to influence several facets of mammalian development, digestion
and disease. Most studies of the microbiota have focused on the bacterial component, but …

[HTML][HTML] In vitro human gut microbiota fermentation models: opportunities, challenges, and pitfalls

J Isenring, L Bircher, A Geirnaert… - Microbiome Research …, 2023 - ncbi.nlm.nih.gov
The human gut microbiota (HGM) plays a pivotal role in health and disease. Consequently,
nutritional and medical research focusing on HGM modulation strategies as a means of …

Macrophage depletion alters bacterial gut microbiota partly through fungal overgrowth in feces that worsens cecal ligation and puncture sepsis mice

P Hiengrach, W Panpetch, A Chindamporn… - Scientific reports, 2022 - nature.com
Because macrophage dysfunction from some emerging therapies might worsen gut-derived
sepsis, cecal ligation and puncture (CLP) sepsis are performed in mice with clodronate …

Alterations of the gut mycobiome in patients with MS

S Shah, A Locca, Y Dorsett, C Cantoni, L Ghezzi… - …, 2021 - thelancet.com
Background The mycobiome is the fungal component of the gut microbiome and is
implicated in several autoimmune diseases. However, its role in MS has not been studied …