The value of reference genomes in the conservation of threatened species

P Brandies, E Peel, CJ Hogg, K Belov - Genes, 2019 - mdpi.com
Conservation initiatives are now more crucial than ever—over a million plant and animal
species are at risk of extinction over the coming decades. The genetic management of …

Translating genomic advances into biodiversity conservation

CJ Hogg - Nature Reviews Genetics, 2024 - nature.com
A key action of the new Global Biodiversity Framework is the maintenance of genetic
diversity in all species to safeguard their adaptive potential. To achieve this goal, a …

Genetic load has potential in large populations but is realized in small inbred populations

S Mathur, JA DeWoody - Evolutionary Applications, 2021 - Wiley Online Library
Populations with higher genetic diversity and larger effective sizes have greater evolutionary
capacity (ie, adaptive potential) to respond to ecological stressors. We are interested in how …

A comparison of pedigree, genetic and genomic estimates of relatedness for informing pairing decisions in two critically endangered birds: Implications for …

SJ Galla, R Moraga, L Brown, S Cleland… - Evolutionary …, 2020 - Wiley Online Library
Conservation management strategies for many highly threatened species include
conservation breeding to prevent extinction and enhance recovery. Pairing decisions for …

From reference genomes to population genomics: comparing three reference-aligned reduced-representation sequencing pipelines in two wildlife species

B Wright, KA Farquharson, EA McLennan, K Belov… - BMC genomics, 2019 - Springer
Background Recent advances in genomics have greatly increased research opportunities
for non-model species. For wildlife, a growing availability of reference genomes means that …

A demonstration of conservation genomics for threatened species management

BR Wright, KA Farquharson… - Molecular Ecology …, 2020 - Wiley Online Library
As species extinction rates increase, genomics provides a powerful tool to support intensive
management of threatened species. We use the Tasmanian devil (Sarcophilus harrisii) to …

Genomic data of different resolutions reveal consistent inbreeding estimates but contrasting homozygosity landscapes for the threatened Aotearoa New Zealand hihi

L Duntsch, A Whibley, P Brekke, JG Ewen… - Molecular …, 2021 - Wiley Online Library
Inbreeding can lead to a loss of heterozygosity in a population and when combined with
genetic drift may reduce the adaptive potential of a species. However, there is uncertainty …

Genomics identifies koala populations at risk across eastern Australia

EA McLennan, TGL Kovacs, LW Silver… - Ecological …, 2024 - Wiley Online Library
Koalas are an iconic, endangered, Australian marsupial. Disease, habitat destruction, and
catastrophic mega‐fires have reduced koalas to remnant patches of their former range. With …

Restoring faith in conservation action: Maintaining wild genetic diversity through the Tasmanian devil insurance program

KA Farquharson, EA McLennan, Y Cheng, L Alexander… - Iscience, 2022 - cell.com
Conservation breeding programs aim to maintain 90% wild genetic diversity, but rarely
assess functional diversity. Here, we compare both genome-wide and functional diversity (in …

Genomic signatures of inbreeding in a critically endangered parrot, the kākāpō

Y Foster, L Dutoit, S Grosser, N Dussex, BJ Foster… - G3, 2021 - academic.oup.com
Events of inbreeding are inevitable in critically endangered species. Reduced population
sizes and unique life-history traits can increase the severity of inbreeding, leading to …