Recent advancements in biomarkers, therapeutics, and associated challenges in acute myeloid leukemia

SK Prajapati, N Kumari, D Bhowmik, R Gupta - Annals of Hematology, 2024 - Springer
Acute myeloid leukemia (AML) is a common type of leukemia that has a high mortality rate.
The reasons for high mortality in patients with AML are therapeutic resistance, limited ability …

[PDF][PDF] Incidence of acute and chronic forms of leukemia in Haryana

R Rathee, M Vashist, A Kumar, S Singh - Int J Pharm Pharm Sci, 2014 - researchgate.net
Objective: The prevalence of leukemia is known to vary throughout the India. The observed
geographic variation in incidence remains unexplained as yet. Previous studies have shown …

Incidence and prognostic importance of molecular genetic defects in children with acute myeloblastic leukemia

M Kömür, F Erbey, I Bayram… - Asian Pac J Cancer Prev, 2010 - journal.waocp.org
Introduction: Acute myeloblastic leukemia (AML) accounts for 15 to 25 percent of childhood
acute leukemias. The most common genetic abnormalities seen in pediatric AML patients …

FLT3 and NPM1 mutations in a cohort of AML patients and detection of a novel mutation in tyrosine kinase domain of FLT3 gene from Western India

K Ghosh, S Swaminathan, M Madkaikar, M Gupta… - Annals of …, 2012 - Springer
Acute myeloid leukemia (AML) is an aggressive hematological disorder characterized by the
loss of ability of the hematopoietic progenitor cells to differentiate and proliferate normally …

High fms-like tyrosine kinase-3 (FLT3) receptor surface expression predicts poor outcome in FLT3 internal tandem duplication (ITD) negative patients in adult acute …

SK Sharawat, V Raina, L Kumar… - Indian Journal of …, 2016 - journals.lww.com
Methods: Total 51 consecutive de novo AML patients aged 18-60 yr were enrolled in the
study. FLT3 ITD was detected by polymerase chain reaction (PCR); flowcytometry and qPCR …

[HTML][HTML] Distribution of fusion transcripts and its clinical impact in patients with acute myeloid leukemia in Sudan

ARM Muddathir, TAM Hamid, EM Elamin… - … Journal of Health …, 2021 - ncbi.nlm.nih.gov
Objective: Acute myeloid leukemia (AML) is a common malignant disorder of hematopoietic
progenitor cells that caused by chromosomal translocation and the formation of fusion …

FLT3-ITD mutation in relation to FLT3 expression in pediatric AML: a prospective study from India

SK Sharawat, R Bakhshi, S Vishnubhatla… - Pediatric Hematology …, 2014 - Taylor & Francis
There is lack of data with regard to FLT3 expression in FLT3-ITD positive pediatric AML
patients. Further, FLT3-ITD has not been systematically analyzed for outcome from Indian …

[PDF][PDF] Pattern of leukaemias in a tertiary care hospital–a 5 years retrospective study of 103 cases

RS Laishram, NB Singh, S Laishram, P Kipgen… - Ind Med …, 2013 - researchgate.net
Objective: To study the distribution of various types of leukaemia in the RIMS Hospital in
terms of types, age, sex and among various ethnic groups. Material and Method: It'sa …

[HTML][HTML] RUNX1-RUNX1T1: comportamiento en pacientes con leucemia mieloide aguda en nuestro medio

H Garrote Santana, AM Amor Vigil… - Revista Cubana de …, 2015 - scielo.sld.cu
Introducción: el continuo desarrollo molecular ha restado protagonismo a otras
clasificaciones de la leucemia mieloide aguda (LMA) basadas en la morfología e …

Gen de fusión AML1-ETO: particularidades en la leucemia mieloide aguda

H Garrote Santana, AM Amor Vigil… - Revista Cubana de …, 2014 - scielo.sld.cu
La leucemia mieloide aguda (LMA) es una enfermedad neoplásica de la médula ósea en la
que los pacientes con la translocación (8; 21) representan un subgrupo con características …