Secretory Products of Trichinella spiralis Muscle Larvae and Immunomodulation: Implication for Autoimmune Diseases, Allergies, and Malignancies

L Sofronic-Milosavljevic, N Ilic, E Pinelli… - Journal of …, 2015 - Wiley Online Library
Trichinella spiralis has the unique ability to make itself “at home” by creating and hiding in a
new type of cell in the host body that is the nurse cell. From this immunologically privileged …

Parasites as negative regulators of cancer

BE Callejas, D Martínez-Saucedo… - Bioscience …, 2018 - portlandpress.com
Several environmental factors (chemical, physical, and biological) can cause the initiation,
promotion, and progression of cancer. Regarding the biological factors, several studies have …

[HTML][HTML] Trichinella spiralis as a potential antitumor agent: An update

S Sadr, Z Yousefsani, PA Simab… - World's Veterinary …, 2023 - cyberleninka.ru
Due to the limited success of therapeutic strategies in treating tumors, a new practical potent
approach is needed. This review aimed to investigate previous literature related to tumors …

[HTML][HTML] Trichinella-induced immunomodulation: another tale of helminth success

F Bruschi, DS Ashour, AA Othman - Food and Waterborne Parasitology, 2022 - Elsevier
Trichinella spiralis is a unique parasite in that both the adults and larvae survive in two
different intracellular niches in the same host. The immune response, albeit intense, is highly …

Suppression of the growth and metastasis of mouse melanoma by Taenia crassiceps and Mesocestoides corti tapeworms

M Schreiber, T Macháček, V Vajs, B Šmídová… - Frontiers in …, 2024 - frontiersin.org
Cancer is still one of the leading causes of death, with an estimated 19.3 million new cases
every year. Our paper presents the tumor-suppressing effect of Taenia crassiceps and …

Parasites as potential targets for cancer immunotherapy

M Yousefi, M Akbari, M Hadipour, AB Dehkordi… - Journal of Cancer …, 2023 - Springer
Parasites and cancers have some common antigens. Much scientific evidence in the human
population, animal models, and in vitro experiments exhibit that parasites have significant …

Trichinella spiralis: inflammation modulator

J Ding, X Liu, X Bai, Y Wang, J Li, C Wang… - Journal of …, 2020 - cambridge.org
The hygiene hypothesis posits that the decreased incidence of parasitic infection in
developed countries may underlie an increased prevalence of allergic and autoimmune …

Neospora caninum inhibits tumor development by activating the immune response and destroying tumor cells in a B16F10 melanoma model

X Li, M Qi, K He, H Liu, W Yan, L Zhao, Y Jia, L He… - Parasites & …, 2022 - Springer
Background Melanoma is a malignant tumor with a high mortality rate. Some
microorganisms have been shown to activate the immune system and limit cancer …

Parasites revive hope for cancer therapy

MM Eissa, AE Salem, N El Skhawy - European Journal of Medical …, 2024 - Springer
Parasites have attained a life-long stigma of being detrimental organisms with deleterious
outcomes. Yet, recently, a creditable twist was verified that can dramatically change our …

[HTML][HTML] Parasite and cancer relationship

F Çelik, S Şimşek - Parasite, 2022 - turkiyeparazitolderg.org
Cancer is a life-threatening disease that occurs as a result of the uncontrolled proliferation of
cells in any organ or tissue of the body. Parasites are dangerous organisms that can cause …