Dynamic, yet structured: the cell membrane three decades after the Singer–Nicolson model

G Vereb, J Szöllősi, J Matko, P Nagy… - Proceedings of the …, 2003 - National Acad Sciences
The fluid mosaic membrane model proved to be a very useful hypothesis in explaining
many, but certainly not all, phenomena taking place in biological membranes. New …

Integrin and cadherin clusters: A robust way to organize adhesions for cell mechanics

R Changede, M Sheetz - BioEssays, 2017 - Wiley Online Library
Recent studies at the nanometer scale have revealed that relatively uniform clusters of
adhesion proteins (50–100 nm) constitute the modular units of cell adhesion sites in both …

Dual-color superresolution imaging of genetically expressed probes within individual adhesion complexes

H Shroff, CG Galbraith, JA Galbraith… - Proceedings of the …, 2007 - National Acad Sciences
Accurate determination of the relative positions of proteins within localized regions of the cell
is essential for understanding their biological function. Although fluorescent fusion proteins …

[HTML][HTML] Properties of lipid microdomains in a muscle cell membrane visualized by single molecule microscopy

GJ Schütz, G Kada, VP Pastushenko… - The EMBO journal, 2000 - embopress.org
The lateral motion of single fluorescence labeled lipid molecules was imaged in native cell
membranes on a millisecond time scale and with positional accuracy of∼ 50 nm, using …

Biologically inspired design of nanoparticle artificial antigen-presenting cells for immunomodulation

JW Hickey, FP Vicente, GP Howard, HQ Mao… - Nano …, 2017 - ACS Publications
Particles engineered to engage and interact with cell surface ligands and to modulate cells
can be harnessed to explore basic biological questions as well as to devise cellular …

Advances in image correlation spectroscopy: measuring number densities, aggregation states, and dynamics of fluorescently labeled macromolecules in cells

DL Kolin, PW Wiseman - Cell biochemistry and biophysics, 2007 - Springer
A brief historical outline of fluorescence fluctuation correlation techniques is presented,
followed by an in-depth review of the theory and development of image correlation …

Dynamics in the plasma membrane: how to combine fluidity and order

D Marguet, PF Lenne, H Rigneault, HT He - The EMBO journal, 2006 - embopress.org
Cell membranes are fascinating supramolecular aggregates that not only form a barrier
between compartments but also harbor many chemical reactions essential to the existence …

Phase separation in biological membranes: integration of theory and experiment

EL Elson, E Fried, JE Dolbow… - Annual review of …, 2010 - annualreviews.org
Lipid bilayer model membranes that contain a single lipid species can undergo transitions
between ordered and disordered phases, and membranes that contain a mixture of lipid …

Dynamics of the actin cytoskeleton mediates receptor cross talk: An emerging concept in tuning receptor signaling

PK Mattila, FD Batista, B Treanor - Journal of Cell Biology, 2016 - rupress.org
Recent evidence implicates the actin cytoskeleton in the control of receptor signaling. This
may be of particular importance in the context of immune receptors, such as the B cell …

Image correlation spectroscopy of multiphoton images correlates with collagen mechanical properties

CB Raub, J Unruh, V Suresh, T Krasieva, T Lindmo… - Biophysical journal, 2008 - cell.com
Multiphoton microscopy (MPM) holds promise as a noninvasive imaging technique for
characterizing collagen structure, and thus mechanical properties, through imaging second …