[HTML][HTML] Multiscale modeling of bone tissue mechanobiology

JM García-Aznar, G Nasello, S Hervas-Raluy… - Bone, 2021 - Elsevier
Mechanical environment has a crucial role in our organism at the different levels, ranging
from cells to tissues and our own organs. This regulatory role is especially relevant for …

Computationally designed lattices with tuned properties for tissue engineering using 3D printing

PF Egan, VC Gonella, M Engensperger, SJ Ferguson… - PloS one, 2017 - journals.plos.org
Tissue scaffolds provide structural support while facilitating tissue growth, but are
challenging to design due to diverse property trade-offs. Here, a computational approach …

Combined experimental and computational characterization of crosslinked collagen-based hydrogels

C Valero, H Amaveda, M Mora, JM García-Aznar - PLoS One, 2018 - journals.plos.org
Collagen hydrogels are widely used for in-vitro experiments and tissue engineering
applications. Their use has been extended due to their biocompatibility with cells and their …

Experimental characterization and computational modeling of hydrogel cross-linking for bioprinting applications

A Hajikhani, F Scocozza, M Conti… - … journal of artificial …, 2019 - journals.sagepub.com
Alginate-based hydrogels are extensively used to create bioinks for bioprinting, due to their
biocompatibility, low toxicity, low costs, and slight gelling. Modeling of bioprinting process …

[HTML][HTML] The role of nuclear mechanics in cell deformation under creeping flows

F Serrano-Alcalde, JM García-Aznar… - Journal of theoretical …, 2017 - Elsevier
Despite the relevant regulatory role that nuclear deformation plays in cell behaviour, a
thorough understanding of how fluid flow modulates the deformation of the cell nucleus in …

Exploring cardiac form and function: A length‐scale computational biology approach

WF Sherman, A Grosberg - Wiley Interdisciplinary Reviews …, 2020 - Wiley Online Library
The ability to adequately pump blood throughout the body is the result of tightly regulated
feedback mechanisms that exist across many spatial scales in the heart. Diseases which …

Cultivated meat modeling consortium: Inaugural meeting whitepaper

S Kahan, J Camphuijsen, C Cannistra, G Potter… - Authorea …, 2020 - authorea.com
The broad environmental, societal and animal welfare issues associated with large-scale
animal protein production are well-documented, and cultivated meat represents a potentially …

[PDF][PDF] Bone regeneration in patient-specific scaffolds from microfluidics to computational simulation

JM García Aznar, H Van Oosterwyck - 2021 - zaguan.unizar.es
Musculoskeletal disorders and related bone diseases are one of the major causes of pain
and disability, resulting in a social and economical burden for our society. When the joint …

[图书][B] Predicting Individual Cardiomyocyte Myofibril Organization In Spatially Constrained Cells

W Sherman - 2020 - search.proquest.com
Through a variety of mechanisms, a healthy heart is able to regulate its structure and
dynamics across multiple length scales. Disruption of these mechanisms can have a …

[引用][C] Bioengenharia e Nanosistemas

ATPB Laranjeira - 2019