Recent developments of quinolone-based derivatives and their activities against Escherichia coli

F Gao, P Wang, H Yang, Q Miao, L Ma, G Lu - European Journal of …, 2018 - Elsevier
Escherichia coli (E. coli) is the most common pathogen in both hospital and community
settings, and is capable of causing infections that can lead to serious consequences …

A panoramic review of benzimidazole derivatives and their potential biological activity

H Hernández-López… - Mini Reviews in …, 2022 - ingentaconnect.com
The therapeutic potential of the benzimidazole nucleus has been recognized since 1944,
and it is an important heterocycle system due to its presence in a wide range of bioactive …

Microwave assisted reactions of azaheterocycles formedicinal chemistry applications

D Amariucai-Mantu, V Mangalagiu, R Danac… - Molecules, 2020 - mdpi.com
Microwave (MW) assisted reactions have became a powerful tool in azaheterocycles
chemistry during the last decades. Five and six membered ring azaheterocycles are …

Thiophene ring-opening reactions. Direct access to the synthesis of 1, 3, 4-thiadiazoline-(condenced) pyridone hybrids

MM Abadleh, AH Abdullah, FF Awwadi… - Tetrahedron, 2021 - Elsevier
The reaction of N'-(aryl) benzothiohydrazides with 2-chloro-7-cyclopropyl-3-nitro-4-
oxothieno [2, 3-b] pyridine-5-carboxylic ester/acid in the presence of triethylamine furnished …

Synthesis and Anticancer Activity of 1‐(Ethyl/Methyl)‐7‐(p‐Methoxybenzyl Amino) and 7‐Amino‐6‐Fluoroquinolone‐Boron Difluoride Complexes

H Hernández‐López, CJ Tejada‐Rodríguez… - …, 2023 - Wiley Online Library
Abstract Novel 1‐(ethyl/methyl)‐7‐(p‐methoxybenzyl amino) and 7‐amino‐6‐
fluoroquinolone‐boron difluoride complexes were synthesized, and their biological activity …

Synthesis and applications of imidazoquinolines: A Review

HG Bazin, LS Bess, MT Livesay - Organic Preparations and …, 2018 - Taylor & Francis
Imidazoquinolines are heterocylic scaffolds resulting from the fusion between the 5-
membered ring imidazole and the benzopyridine ring, quinoline (Figure 1). Such fused …

Heterocycles [h]-fused onto 4-oxoquinoline-3-carboxylic acid. Part XII: synthesis of 5-fluoro-7-oxodihydo[1,3,4]thiadiazino [5,6-h]quinoline-8-carboxylic acid and ester

MM El-Abadelah, MM Abadleh, FF Awwadi… - … für Naturforschung B, 2018 - degruyter.com
Direct interaction of dithizone with 7-chloro-6-fluoro-8-nitro-4-oxoquinoline-3-carboxylic acid
or with its ester delivered the corresponding novel 1, 3, 4-thiadiazino [5, 6-h] quinoline 3 …

Síntesis y evaluación docking de complejos 1-(etil/metil)-6-fluoroquinolona-boro con modificaciones en C-7 y/o C-8

CJ Tejada Rodríguez - 2021 - repositorioinstitucional.uaslp.mx
El presente trabajo plantea una ruta eficiente para la síntesis de complejos 7-amino-8-nitro-
6-fluoroquinolona boro 169 y 170 obteniendo un 71% y 66% de rendimiento …