Experimental autoimmune encephalomyelitis (EAE) is a demyelinating disease of the
central nervous system and is an animal model of multiple sclerosis (MS). Although the …

This work reports molecular dynamics studies at the receptor level of the immunodominant
myelin basic protein (MBP) epitope 87–99 implicated in multiple sclerosis, and its …

This article describes the rational design, synthesis and pharmacological properties of
amide-linked cyclic analogues of Luteinizing Hormone-Releasing Hormone (LHRH) with …

The solution models of cyclo (87− 99) MBP87-99, cyclo (87− 99)[Ala91, 96] MBP87-99, and
cyclo (87− 99)[Arg91, Ala96] MBP87-99 have been determined through 2D NMR …

Abstract Myelin basic protein peptide 83–99 (MBP83–99) is the most immunodominant
epitope playing a significant role in the multiple sclerosis (MS), an autoimmune disease of …

The two new synthetic analogues of the MBP 83–99 epitope substituted at Lys 91 (primary
TCR contact) with Phe [MBP 83–99 (Phe 91)] or Tyr [MBP 83–99 (Tyr 91)], have been …

The knowledge of a bioactive conformation of a known lead or potential lead compounds
undoubtedly will offer a save of money and time consuming to pharmaceutical companies …

The two new synthetic analogues of the MBP83–99 epitope substituted at Lys91 (primary
TCR contact) with Phe [MBP83–99 (Phe91)] or Tyr [MBP83–99 (Tyr91)], have been …

The two new synthetic analogues of the MBP^ sub 83-99^ epitope substituted at Lys^ sup
91^(primary TCR contact) with Phe [MBP^ sub 83-99^(Phe^ sup 91^)] or Tyr [MBP^ sub 83 …

The two new synthetic analogues of the MBP epitope substituted at Lys (primary TCR
contact) with Phe [MBP (Phe)] or Tyr [MBP (Tyr)], have been structurally elucidated using 1D …