Lipid nanoparticles─ from liposomes to mRNA vaccine delivery, a landscape of research diversity and advancement

R Tenchov, R Bird, AE Curtze, Q Zhou - ACS nano, 2021 - ACS Publications
Lipid nanoparticles (LNPs) have emerged across the pharmaceutical industry as promising
vehicles to deliver a variety of therapeutics. Currently in the spotlight as vital components of …

[HTML][HTML] Stimuli-responsive liposomal nanoformulations in cancer therapy: Pre-clinical & clinical approaches

M Ashrafizadeh, M Delfi, A Zarrabi, A Bigham… - Journal of controlled …, 2022 - Elsevier
The site-specific delivery of antitumor agents is of importance for providing effective cancer
suppression. Poor bioavailability of anticancer compounds and the presence of biological …

Stimuli-responsive polymeric nanocarriers for drug delivery, imaging, and theragnosis

SS Das, P Bharadwaj, M Bilal, M Barani, A Rahdar… - Polymers, 2020 - mdpi.com
In the past few decades, polymeric nanocarriers have been recognized as promising tools
and have gained attention from researchers for their potential to efficiently deliver bioactive …

Emerging blood–brain-barrier-crossing nanotechnology for brain cancer theranostics

W Tang, W Fan, J Lau, L Deng, Z Shen… - Chemical Society …, 2019 - pubs.rsc.org
Brain cancer, especially the most common type of glioblastoma, is highly invasive and
known as one of the most devastating and deadly neoplasms. Despite surgical and medical …

Recent advances in nanomaterial-based synergistic combination cancer immunotherapy

W Sang, Z Zhang, Y Dai, X Chen - Chemical Society Reviews, 2019 - pubs.rsc.org
In recent years, conventional treatments including surgery, chemotherapy and radiotherapy
have been the main approaches in tumour therapy. Cancer immunotherapy is a new …

Multi‐functional liposome: a powerful theranostic nano‐platform enhancing photodynamic therapy

X Cheng, J Gao, Y Ding, Y Lu, Q Wei, D Cui… - Advanced …, 2021 - Wiley Online Library
Although photodynamic therapy (PDT) has promising advantages in almost non‐invasion,
low drug resistance, and low dark toxicity, it still suffers from limitations in the lipophilic …

Surface functionalization and targeting strategies of liposomes in solid tumor therapy: A review

MK Riaz, MA Riaz, X Zhang, C Lin, KH Wong… - International journal of …, 2018 - mdpi.com
Surface functionalization of liposomes can play a key role in overcoming the current
limitations of nanocarriers to treat solid tumors, ie, biological barriers and physiological …

Self‐assembled peptide‐based nanomaterials for biomedical imaging and therapy

GB Qi, YJ Gao, L Wang, H Wang - Advanced materials, 2018 - Wiley Online Library
Peptide‐based materials are one of the most important biomaterials, with diverse structures
and functionalities. Over the past few decades, a self‐assembly strategy is introduced to …

Stimuli‐responsive liposomes for drug delivery

Y Lee, DH Thompson - Wiley Interdisciplinary Reviews …, 2017 - Wiley Online Library
The ultimate goal of drug delivery is to increase the bioavailability and reduce the toxic side
effects of the active pharmaceutical ingredient (API) by releasing them at a specific site of …

Intelligent poly (l-histidine)-based nanovehicles for controlled drug delivery

Y Zhang, I Kim, Y Lu, Y Xu, DG Yu, W Song - Journal of Controlled Release, 2022 - Elsevier
Stimuli-responsive drug delivery systems based on polymeric nanovehicles are among the
most promising treatment regimens for malignant cancers. Such intelligent systems that …