Context Menopause, the permanent cessation of menses, reflects oocyte depletion and loss
of gonadal steroids. It is preceded by a transition state, the perimenopause, which is …

Every woman who lives past midlife will experience menopause, which, by definition, is
complete cessation of ovarian function. This process might occur spontaneously (natural …

“The 2022 Hormone Therapy Position Statement of The North American Menopause
Society”(NAMS) updates “The 2017 Hormone Therapy Position Statement of The North …

Alzheimer disease (AD) is characterized by wide heterogeneity in cognitive and behavioural
syndromes, risk factors and pathophysiological mechanisms. Addressing this phenotypic …

Introduction Precision medicine methodologies and approaches have advanced our
understanding of the clinical presentation, development, progression, and management of …

Virtually all adults with Down syndrome (DS) show the neuropathological changes of
Alzheimer disease (AD) by the age of 40 years. This association is partially due to …

Abstract The International Menopause Society (IMS) has produced these new 2016
recommendations on women's midlife health and menopause hormone therapy (MHT) to …

Alzheimer's disease (AD) dementia is the most common form of dementia, comprising 60 to
70 percent of all cases. AD is a progressive neurodegenerative disease that causes memory …

Men and women exhibit differences in the development and progression of Alzheimer's
disease (AD). The factors underlying the sex differences in AD are not well understood. This …

Major depressive disorder is a common psychiatric disorder associated with marked
suffering, morbidity, mortality, and cost. The World Health Organization projects that by 2030 …