Artificial intelligence for drug discovery: Are we there yet?

C Hasselgren, TI Oprea - Annual Review of Pharmacology and …, 2024 - annualreviews.org
Drug discovery is adapting to novel technologies such as data science, informatics, and
artificial intelligence (AI) to accelerate effective treatment development while reducing costs …

Link prediction techniques, applications, and performance: A survey

A Kumar, SS Singh, K Singh, B Biswas - Physica A: Statistical Mechanics …, 2020 - Elsevier
Link prediction finds missing links (in static networks) or predicts the likelihood of future links
(in dynamic networks). The latter definition is useful in network evolution (Wang et al., 2011; …

Circular RNAs and complex diseases: from experimental results to computational models

CC Wang, CD Han, Q Zhao, X Chen - Briefings in bioinformatics, 2021 - academic.oup.com
Circular RNAs (circRNAs) are a class of single-stranded, covalently closed RNA molecules
with a variety of biological functions. Studies have shown that circRNAs are involved in a …

Hin2vec: Explore meta-paths in heterogeneous information networks for representation learning

T Fu, WC Lee, Z Lei - Proceedings of the 2017 ACM on Conference on …, 2017 - dl.acm.org
In this paper, we propose a novel representation learning framework, namely HIN2Vec, for
heterogeneous information networks (HINs). The core of the proposed framework is a neural …

[图书][B] Recommender systems

CC Aggarwal - 2016 - Springer
“Nature shows us only the tail of the lion. But I do not doubt that the lion belongs to it even
though he cannot at once reveal himself because of his enormous size.”–Albert Einstein The …

A survey of heterogeneous information network analysis

C Shi, Y Li, J Zhang, Y Sun… - IEEE Transactions on …, 2016 - ieeexplore.ieee.org
Most real systems consist of a large number of interacting, multi-typed components, while
most contemporary researches model them as homogeneous information networks, without …

Systematic integration of biomedical knowledge prioritizes drugs for repurposing

DS Himmelstein, A Lizee, C Hessler, L Brueggeman… - Elife, 2017 - elifesciences.org
The ability to computationally predict whether a compound treats a disease would improve
the economy and success rate of drug approval. This study describes Project Rephetio to …

Attention models in graphs: A survey

JB Lee, RA Rossi, S Kim, NK Ahmed… - ACM Transactions on …, 2019 - dl.acm.org
Graph-structured data arise naturally in many different application domains. By representing
data as graphs, we can capture entities (ie, nodes) as well as their relationships (ie, edges) …

Academic social networks: Modeling, analysis, mining and applications

X Kong, Y Shi, S Yu, J Liu, F Xia - Journal of Network and Computer …, 2019 - Elsevier
In the fast-growing scholarly big data background, social network technologies have recently
aroused widespread attention in academia and industry. The concept of academic social …

Link prediction in social networks: the state-of-the-art

P Wang, BW Xu, YR Wu, XY Zhou - arXiv preprint arXiv:1411.5118, 2014 - arxiv.org
In social networks, link prediction predicts missing links in current networks and new or
dissolution links in future networks, is important for mining and analyzing the evolution of …