A global overview of genetically interpretable multimorbidities among common diseases in the UK Biobank

G Dong, J Feng, F Sun, J Chen, XM Zhao - Genome medicine, 2021 - Springer
Background Multimorbidities greatly increase the global health burdens, but the landscapes
of their genetic risks have not been systematically investigated. Methods We used the …

Interleukin-17 links inflammatory cross-talks between comorbid psoriasis and atherosclerosis

Y Wang, J Zang, C Liu, Z Yan, D Shi - Frontiers in Immunology, 2022 - frontiersin.org
Psoriasis is a chronic, systemic, immune-mediated inflammatory disorder that is associated
with a significantly increased risk of cardiovascular disease (CVD). Studies have shown that …

Machine learning models for prediction of co-occurrence of diabetes and cardiovascular diseases: a retrospective cohort study

AS Abdalrada, J Abawajy, T Al-Quraishi… - Journal of Diabetes & …, 2022 - Springer
Background Diabetic mellitus (DM) and cardiovascular diseases (CVD) cause significant
healthcare burden globally and often co-exists. Current approaches often fail to identify …

Analysis of disease comorbidity patterns in a large-scale China population

M Guo, Y Yu, T Wen, X Zhang, B Liu, J Zhang… - BMC medical …, 2019 - Springer
Background Disease comorbidity is popular and has significant indications for disease
progress and management. We aim to detect the general disease comorbidity patterns in …

NSL2CD: identifying potential circRNA–disease associations based on network embedding and subspace learning

Q Xiao, Y Fu, Y Yang, J Dai, J Luo - Briefings in Bioinformatics, 2021 - academic.oup.com
Many studies have evidenced that circular RNAs (circRNAs) are important regulators in
various pathological processes and play vital roles in many human diseases, which could …

Learning from low-rank multimodal representations for predicting disease-drug associations

P Hu, Y Huang, J Mei, H Leung, Z Chen… - BMC medical informatics …, 2021 - Springer
Background Disease-drug associations provide essential information for drug discovery and
disease treatment. Many disease-drug associations remain unobserved or unknown, and …

Relation prediction of co-morbid diseases using knowledge graph completion

S Biswas, P Mitra, KS Rao - IEEE/ACM Transactions on …, 2019 - ieeexplore.ieee.org
Co-morbid disease condition refers to the simultaneous presence of one or more diseases
along with the primary disease. A patient suffering from co-morbid diseases possess more …

MorbidGCN: prediction of multimorbidity with a graph convolutional network based on integration of population phenotypes and disease network

G Dong, ZC Zhang, J Feng… - Briefings in …, 2022 - academic.oup.com
Exploring multimorbidity relationships among diseases is of great importance for
understanding their shared mechanisms, precise diagnosis and treatment. However, the …

Constructing disease similarity networks based on disease module theory

P Ni, J Wang, P Zhong, Y Li, FX Wu… - IEEE/ACM transactions …, 2018 - ieeexplore.ieee.org
Quantifying the associations between diseases is now playing an important role in modern
biology and medicine. Actually discovering associations between diseases could help us …

A novel approach for disease comorbidity prediction using weighted association rule mining

KS Lakshmi, G Vadivu - Journal of Ambient Intelligence and Humanized …, 2019 - Springer
Disease comorbidity prediction has gained the attention of many researchers during the past
years. Bulk creation of clinical data in the form of electronic health records (EHRs) and …