This brief review summarizes 60 years of conceptual advances that have demonstrated a role for active changes in neuronal connectivity as a controller of behavior and behavioral …
J Lisman, R Yasuda, S Raghavachari - Nature reviews neuroscience, 2012 - nature.com
Long-term potentiation (LTP) of synaptic strength occurs during learning and can last for long periods, making it a probable mechanism for memory storage. LTP induction results in …
J Lisman, H Schulman, H Cline - Nature Reviews Neuroscience, 2002 - nature.com
Long-term potentiation (LTP) in the CA1 region of the hippocampus has been the primary model by which to study the cellular and molecular basis of memory. Calcium/calmodulin …
A growing body of scientific evidence indicates that exercise has a positive impact on human health, including neurological health. Aerobic exercise, which is supposed to enhance …
The calcium-calmodulin–dependent kinase II (CaMKII) is required for hippocampal long- term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM) …
Long-term potentiation (LTP) is arguably the most compelling cellular model for learning and memory. While the mechanisms underlying the induction of LTP ('learning') are well …
HK Lee, M Barbarosie, K Kameyama, MF Bear… - Nature, 2000 - nature.com
Bidirectional changes in the efficacy of neuronal synaptic transmission, such as hippocampal long-term potentiation (LTP) and long-term depression (LTD), are thought to …
How can short-lived molecules selectively maintain the potentiation of activated synapses to sustain long-term memory? Here, we find kidney and brain expressed adaptor protein …
A Hudmon, H Schulman - Annual review of biochemistry, 2002 - annualreviews.org
▪ Abstract Highly enriched in brain tissue and present throughout the body, Ca2+/calmodulin- dependent protein kinase II (CaMKII) is central to the coordination and execution of Ca2+ …