Cancer survivorship

CL Shapiro - New England Journal of Medicine, 2018 - Mass Medical Soc
Cancer Survivorship Improvements in cancer screening, early detection, and treatment are
resulting in increased numbers of patients cured of cancer. These persons face a wide …

Therapy-related myeloid neoplasms: when genetics and environment collide

ME McNerney, LA Godley, MM Le Beau - Nature Reviews Cancer, 2017 - nature.com
Therapy-related myeloid neoplasms (t-MN) arise as a late effect of chemotherapy and/or
radiation administered for a primary condition, typically a malignant disease, solid organ …

Association of chemotherapy for solid tumors with development of therapy-related myelodysplastic syndrome or acute myeloid leukemia in the modern era

LM Morton, GM Dores, SJ Schonfeld, MS Linet… - JAMA …, 2019 - jamanetwork.com
Importance Therapy-related myelodysplastic syndrome or acute myeloid leukemia
(tMDS/AML) is a rare, usually fatal complication of chemotherapy, including certain …

Risk of hematologic malignancies after radioiodine treatment of well-differentiated thyroid cancer

RJ Molenaar, S Sidana, T Radivoyevitch… - Journal of clinical …, 2018 - ascopubs.org
Purpose To investigate the risk and outcomes of second hematologic malignancies (SHMs)
in a population-based cohort of patients with well-differentiated thyroid cancer (WDTC) …

[PDF][PDF] Acute Leukaemia: A Sudden Killer to Human Beings

OE Ifeanyi - EC Emergency Medicine and Critical Care, 2020 - academia.edu
Leukaemia is among the leading haematological disorders causing the deaths of many in
the society. This paper was reviewed to update the dangers associated with acute …

Elevated mutational age in blood of children treated for cancer contributes to therapy-related myeloid neoplasms

EJM Bertrums, AKM Rosendahl Huber, JK de Kanter… - Cancer discovery, 2022 - AACR
Childhood cancer survivors are confronted with various chronic health conditions like
therapy-related malignancies. However, it is unclear how exposure to chemotherapy …

[HTML][HTML] Pathophysiology of acute myeloid leukemia

F Wachter, Y Pikman - Acta Haematologica, 2024 - karger.com
Background: Acute myeloid leukemia (AML) is a biologically heterogenous disease arising
in clonally proliferating hematopoietic stem cells. Sequential acquisition of mutations leads …

Risk of acute myeloid leukemia and myelodysplastic syndrome after autotransplants for lymphomas and plasma cell myeloma

T Radivoyevitch, RM Dean, BE Shaw, R Brazauskas… - Leukemia research, 2018 - Elsevier
Background Exposures to DNA-damaging drugs and ionizing radiations increase risks of
acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). Methods 9028 …

Artificial intelligence reveals the predictions of hematological indexes in children with acute leukemia

ZJ Cheng, H Li, M Liu, X Fu, L Liu, Z Liang, H Gan… - BMC cancer, 2024 - Springer
Childhood leukemia is a prevalent form of pediatric cancer, with acute lymphoblastic
leukemia (ALL) and acute myeloid leukemia (AML) being the primary manifestations. Timely …

Role of germline predisposition to therapy-related myeloid neoplasms

A Baranwal, CN Hahn, MV Shah… - Current Hematologic …, 2022 - Springer
Abstract Purpose of Review Therapy-related myeloid neoplasms (t-MNs) are aggressive
leukemias that develop following exposure to DNA-damaging agents. A subset of patients …