[HTML][HTML] Neuroprosthetics: from sensorimotor to cognitive disorders

A Gupta, N Vardalakis, FB Wagner - Communications biology, 2023 - nature.com
Neuroprosthetics is a multidisciplinary field at the interface between neurosciences and
biomedical engineering, which aims at replacing or modulating parts of the nervous system …

Neuropixels 2.0: A miniaturized high-density probe for stable, long-term brain recordings

NA Steinmetz, C Aydin, A Lebedeva, M Okun… - Science, 2021 - science.org
INTRODUCTION Electrode arrays based on complementary metal-oxide semiconductor
silicon fabrication technology, such as Neuropixels probes, have enabled recordings of …

[HTML][HTML] Emerging Penetrating Neural Electrodes: In Pursuit of Large Scale and Longevity

L Luan, R Yin, H Zhu, C Xie - Annual review of biomedical …, 2023 - annualreviews.org
Penetrating neural electrodes provide a powerful approach to decipher brain circuitry by
allowing for time-resolved electrical detections of individual action potentials. This unique …

[HTML][HTML] Coupling between motor cortex and striatum increases during sleep over long-term skill learning

SM Lemke, DS Ramanathan, D Darevksy, D Egert… - Elife, 2021 - elifesciences.org
The strength of cortical connectivity to the striatum influences the balance between
behavioral variability and stability. Learning to consistently produce a skilled action requires …

[HTML][HTML] Information flow between motor cortex and striatum reverses during skill learning

SM Lemke, M Celotto, R Maffulli, K Ganguly, S Panzeri - Current Biology, 2024 - cell.com
The coordination of neural activity across brain areas during a specific behavior is often
interpreted as neural communication involved in controlling the behavior. However, whether …

[HTML][HTML] Recovery of consolidation after sleep following stroke—interaction of slow waves, spindles, and GABA

J Kim, L Guo, A Hishinuma, S Lemke, DS Ramanathan… - Cell reports, 2022 - cell.com
Sleep is known to promote recovery after stroke. Yet it remains unclear how stroke affects
neural processing during sleep. Using an experimental stroke model in rats along with …

Mechanically adaptive and deployable intracortical probes enable long-term neural electrophysiological recordings

S Wang, Q Jiang, H Liu, C Yu, P Li, G Pan, K Xu… - Proceedings of the …, 2024 - pnas.org
Flexible intracortical probes offer important opportunities for stable neural interfaces by
reducing chronic immune responses, but their advances usually come with challenges of …

Lifetime engineering of bioelectronic implants with mechanically reliable thin film encapsulations

M Niemiec, K Kim - Progress in Biomedical Engineering, 2023 - iopscience.iop.org
While the importance of thin form factor and mechanical tissue biocompatibility has been
made clear for next generation bioelectronic implants, material systems meeting these …

[HTML][HTML] Technological challenges in the development of optogenetic closed-loop therapy approaches in epilepsy and related network disorders of the brain

B Vandekerckhove, J Missinne, K Vonck, P Bauwens… - Micromachines, 2020 - mdpi.com
Epilepsy is a chronic, neurological disorder affecting millions of people every year. The
current available pharmacological and surgical treatments are lacking in overall efficacy and …

[HTML][HTML] Modular data acquisition system for recording activity and electrical stimulation of brain tissue using dedicated electronics

P Jurgielewicz, T Fiutowski, E Kublik, A Skoczeń… - Sensors, 2021 - mdpi.com
In this paper, we present a modular Data Acquisition (DAQ) system for simultaneous
electrical stimulation and recording of brain activity. The DAQ system is designed to work …