[HTML][HTML] The mitochondrial protease OMA1 acts as a metabolic safeguard upon nuclear DNA damage
P Rivera-Mejías, ÁJ Narbona-Pérez, L Hasberg… - Cell Reports, 2023 - cell.com
The metabolic plasticity of mitochondria ensures cell development, differentiation, and
survival. The peptidase OMA1 regulates mitochondrial morphology via OPA1 and stress …
survival. The peptidase OMA1 regulates mitochondrial morphology via OPA1 and stress …
Genome-wide conditional degron libraries for functional genomics
E Gameiro, KA Juárez-Núñez, JJ Fung… - Journal of Cell …, 2025 - rupress.org
Functional genomics with libraries of knockout alleles is limited to non-essential genes and
convoluted by the potential accumulation of suppressor mutations in knockout backgrounds …
convoluted by the potential accumulation of suppressor mutations in knockout backgrounds …
Experimental Evolution of Extreme Resistance to Ionizing Radiation in Escherichia coli after 50 Cycles of Selection
ST Bruckbauer, JD Trimarco, J Martin… - Journal of …, 2019 - Am Soc Microbiol
In previous work (DR Harris et al., J Bacteriol 191: 5240–5252, 2009, https://doi.
org/10.1128/jb. 00502-09; BT Byrne et al., Elife 3: e01322, 2014, https://doi …
org/10.1128/jb. 00502-09; BT Byrne et al., Elife 3: e01322, 2014, https://doi …
Hydroxyurea induces a stress response that alters DNA replication and nucleotide metabolism in Bacillus subtilis
KJ Wozniak, LA Simmons - Journal of bacteriology, 2021 - Am Soc Microbiol
Hydroxyurea (HU) is classified as a ribonucleotide reductase (RNR) inhibitor and has been
widely used to stall DNA replication by depleting deoxyribonucleoside triphosphate (dNTP) …
widely used to stall DNA replication by depleting deoxyribonucleoside triphosphate (dNTP) …
Characteristic effect of hydroxyurea on the higher-order structure of DNA and gene expression
H Ogawa, T Nishio, Y Yoshikawa, K Sadakane… - Scientific Reports, 2024 - nature.com
Hydroxyurea (HU; hydroxycarbamide) is a chemotherapy medication used to treat various
types of cancer and other diseases such as sickle cell anemia. HU inhibits DNA synthesis by …
types of cancer and other diseases such as sickle cell anemia. HU inhibits DNA synthesis by …
Replication rapidly recovers and continues in the presence of hydroxyurea in Escherichia coli
SA Nazaretyan, N Savic, M Sadek… - Journal of …, 2018 - Am Soc Microbiol
In both prokaryotes and eukaryotes, hydroxyurea is suggested to inhibit DNA replication by
inactivating ribonucleotide reductase and depleting deoxyribonucleoside triphosphate …
inactivating ribonucleotide reductase and depleting deoxyribonucleoside triphosphate …
Rational design of bioactive chimeric construct by exploring archaeal antimicrobial peptides: an in silico approach
S Banerjee, S Chakraborty, K Majumder - Biologia, 2022 - Springer
Novel peptide therapeutics have been the cardinal part of modern-day research. Such
therapies are being incorporated to prevent the adverse effects of globally emergent multi …
therapies are being incorporated to prevent the adverse effects of globally emergent multi …
In silico design of bioactive chimeric peptide from archaeal antimicrobial peptides
S Banerjee, S Chakraborty, K Majumder - bioRxiv, 2021 - biorxiv.org
Novel peptide therapeutics have been the cardinal part of modern-day research. Such
therapies are being incorporated to prevent the adverse effects of globally emerging multi …
therapies are being incorporated to prevent the adverse effects of globally emerging multi …
[PDF][PDF] Control of a chemical chaperone by a universally conserved ATPase
HJ Vogel, H Jessen, G Koch - freidok.uni-freiburg.de
SUMMARY The universally conserved YchF/Ola1 ATPases regulate stress response
pathways in prokaryotes and eukaryotes. Deletion of YchF/Ola1 leads to increased …
pathways in prokaryotes and eukaryotes. Deletion of YchF/Ola1 leads to increased …