The status of hepatitis C virus infection among people who inject drugs in the Middle East and North Africa

S Mahmud, GR Mumtaz, H Chemaitelly… - …, 2020 - Wiley Online Library
Background and aims People who inject drugs (PWID) are a key population at high risk of
hepatitis C virus (HCV) infection. The aim of this study was to delineate the epidemiology of …

Hepatitis C virus treatment in children: a challenge for hepatitis C virus elimination

MH El-Sayed, G Indolfi - Seminars in Liver Disease, 2020 - thieme-connect.com
Hepatitis C is a global public health threat. The introduction of direct-acting antivirals (DAAs)
brings the prospect of curing the 71 million people living with the disease, dramatically …

Characterization of the hepatitis C virus epidemic in Pakistan

S Mahmud, Z Al Kanaani, LJ Abu-Raddad - BMC infectious diseases, 2019 - Springer
Background With one in every 20 Pakistanis already infected, Pakistan has the second
largest number of hepatitis C virus (HCV) infections globally. The aim of this study was to …

Treatment as prevention for hepatitis C virus in the Middle East and North Africa: a modeling study

HH Ayoub, S Mahmud, H Chemaitelly… - Frontiers in Public …, 2023 - frontiersin.org
Background Direct-acting antivirals opened an opportunity for eliminating hepatitis C virus
(HCV) infection in the Middle East and North Africa (MENA), the region most affected by …

Characterizing trends and associations for hepatitis C virus antibody prevalence in the Middle East and North Africa: meta-regression analyses

S Mahmud, H Chemaitelly, AS Alaama, JG Hermez… - Scientific Reports, 2022 - nature.com
This study characterized population-level trends and associations with hepatitis C virus
(HCV) antibody (Ab) prevalence in the Middle East and North Africa (MENA). Data source …

[HTML][HTML] Occult hepatitis C virus infection in the Middle East and Eastern Mediterranean countries: A systematic review and meta-analysis

MR Hedayati-Moghaddam, H Soltanian… - World Journal of …, 2021 - ncbi.nlm.nih.gov
BACKGROUND The presence of hepatitis C virus (HCV) RNA in liver tissue or peripheral
blood mononuclear cells with no identified virus genome in the serum has been reported …

BCL-3 promotes a cancer stem cell phenotype by enhancing β-catenin signalling in colorectal tumour cells

DN Legge, AP Shephard, TJ Collard… - Disease Models & …, 2019 - journals.biologists.com
To decrease bowel cancer incidence and improve survival, we need to understand the
mechanisms that drive tumorigenesis. Recently, B-cell lymphoma 3 (BCL-3; a key regulator …

[HTML][HTML] Sub-genotypes of hepatitis C virus in the Middle East and North Africa: Patterns of distribution and temporal changes

RY Athamneh, R Abudalo, M Sallam, A Alqudah… - Infection, Genetics and …, 2023 - Elsevier
Infection with the hepatitis C virus (HCV) remains a considerable public health concern in
the Middle East and North Africa (MENA). The objectives of this study were to analyze the …

Hepatitis C virus transmission among people who inject drugs in the Middle East and North Africa: mathematical modeling analyses of incidence and intervention …

M Makhoul, GR Mumtaz, HH Ayoub, MS Jamil… - …, 2025 - thelancet.com
Summary Background The Middle East and North Africa (MENA) region is the most affected
by hepatitis C virus (HCV) infection globally. This study aimed to estimate HCV incidence …

Treatment as prevention for hepatitis C virus in Pakistan: mathematical modelling projections

HH Ayoub, LJ Abu-Raddad - BMJ open, 2019 - bmjopen.bmj.com
Objective Direct-acting antivirals have opened an opportunity for controlling hepatitis C virus
(HCV) infection in Pakistan, where 10% of the global infection burden is found. We aimed to …