Red blood cells as therapeutic target to treat sickle cell disease

S Bhatt, DA Argueta, K Gupta… - Antioxidants & Redox …, 2024 - liebertpub.com
Significance: Sickle cell disease (SCD) is the most common inherited diathesis affecting
mostly underserved populations globally. SCD is characterized by chronic pain and fatigue …

Hidden comorbidities in asthma: a perspective for a personalized approach

M Maule, B Olivieri, G Guarnieri… - Journal of Clinical …, 2023 - mdpi.com
Bronchial asthma is the most frequent inflammatory non-communicable condition affecting
the airways worldwide. It is commonly associated with concomitant conditions, which …

Multicenter comparative study of polysomnography outcomes in children with the monogenic disorder sickle cell disease

AS Alishlash, AR Nourani, J Lebensburger… - Journal of Clinical …, 2024 - jcsm.aasm.org
Study Objectives: Sleep-disordered breathing (SDB) is prevalent in children with sickle cell
disease (SCD) and is associated with worse outcomes. This study aims to compare the …

[HTML][HTML] Sickle cell disease and its respiratory complications

MI Khan, N Patel, RT Meda, SP Nuguru, S Rachakonda… - Cureus, 2022 - ncbi.nlm.nih.gov
Sickle cell disease (SCD) is a hematological disorder that is inherited in an autosomal
recessive (AR) fashion. It is caused by mutations in the genes encoding for the globin …

Respiratory manifestations of sickle cell disease in children: a comprehensive review for the pediatrician

L Grigoli, M Maiocchi, L Venditto, M Piazza… - Expert Review of …, 2025 - Taylor & Francis
Introduction Sickle cell disease (SCD) is an inherited hemoglobinopathy characterized by
the production of sickle hemoglobin, leading to red blood cells sickling and hemolysis in …

Lung clearance index may detect early peripheral lung disease in sickle cell Anemia

M Arigliani, FJ Kirkham, S Sahota, M Riley… - Annals of the …, 2022 - atsjournals.org
Rationale: Chronic lung injury is common in sickle cell anemia (SCA) and worsens
outcomes. Sensitive lung function tests might predict reversible disease that might benefit …

The burden of sleep disordered breathing in children with sickle cell disease

I Liguoro, M Arigliani, HL Tan, A Gupta - Pediatric Pulmonology, 2021 - Wiley Online Library
Children with sickle cell disease (SCD) have an increased risk of sleep disordered breathing
(SDB) compared with the general pediatric population. There has been a growing research …

Establishment of a Comprehensive Platform for Sustained Delivery of Yoga Therapy for Sickle Cell Anemia in Rural and Remote Tribal Pocket in India

T Neeraja, RN Mavathur, HA Shukla… - International Journal of …, 2024 - journals.lww.com
Background: Sickle cell anemia (SCA) is the most common inherited genetic red blood cell
disorder, highly prevalent in the tribal population residing in the Central India. The affected …

The 3rd Pan African Thoracic Society (PATS) biennial congress: Lessons learnt to advance lung health in Africa

J Kagima, A Irungu, A Ongaya, B Miheso… - Journal of the Pan …, 2024 - patsjournal.org
Lung health in Africa is of great public health concern. To exchange knowledge,
communicate the latest scientific advances in lung health, build the capacity of young …

Description of a colocated comprehensive care model for people with sickle cell and comorbid pulmonary disease

C Pugh, RN Zeno, J Stanek, M Gillespie… - Journal of Pediatric …, 2023 - journals.lww.com
Comorbid pulmonary complications in people with sickle cell disease (pwSCD) are
associated with high rates of morbidity and mortality, and poor access to care contributes to …