Abstract N6-methyladenosine (m6A) is the most prevalent, abundant and conserved internal
cotranscriptional modification in eukaryotic RNAs, especially within higher eukaryotic cells …

The recent discovery of reversible mRNA methylation has opened a new realm of post-
transcriptional gene regulation in eukaryotes. The identification and functional …

Abstract Background N6-methyladenosine (m6A) methylation, a well-known modification
with new epigenetic functions, has been reported to participate in the tumorigenesis of …

The chemical modification of RNA is a newly discovered epigenetic regulation mechanism
in cells and plays a crucial role in a variety of biological processes. N6-methyladenine (m6A) …

N6-methyladenosine (m6A) epitranscriptional modification has recently gained much
attention. Through the development of m6A sequencing, the molecular mechanism and …

The initiation and progression of diffuse large B-cell lymphoma (DLBCL) is governed by
genetic and epigenetic aberrations. As the most abundant eukaryotic messenger RNA …

Wilms' tumor 1-associating protein (WTAP) is a putative splicing regulator that is thought to
be required for cell cycle progression through the stabilization of cyclin A2 mRNA and …

The biology of acute myelogenous leukemia (AML) is characterized by a block in
differentiation, increase in proliferation and inhibition of apoptosis, all of which when …

N 6-Methyladenosine (m 6 A) RNA modification brings a new dawn for RNA modification
researches in recent years. This posttranscriptional RNA modification is dynamic and …

Glioblastoma (GBM) is a grade IV glioma that is the most malignant brain tumor type.
Currently, there are no effective and sufficient therapeutic strategies for its treatment …