Dental caries is one of the most common bacteria-related oral diseases, and the cariogenic
bacteria play critical roles in its pathogenesis. Antibacterial therapy is regarded as an …

Candida albicans is a symbiotic fungus that commonly colonizes on oral mucosal surfaces
and mainly affects immuno-compromised individuals. Polymicrobial interactions between C …

Background Dental caries is a microbe and sugar-mediated biofilm-dependent oral disease.
Of particular significance, a virulent type of dental caries, known as severe early childhood …

Fungal pathogens have been designated by the World Health Organization as microbial
threats of the highest priority for global health. It remains a major challenge to improve …

Candida albicans, an oral fungal opportunistic pathogen, has shown the ability to colonize
implant surfaces and has been frequently isolated from biofilms associated with dental …

Under natural environmental settings or in the human body, the majority of microorganisms
exist in complex polymicrobial biofilms adhered to abiotic and biotic surfaces. These …

Biofilms are three-dimensional structures formed as a result of microorganism's adhesion on
a biotic or abiotic surface. Once a biofilm is established, it is onerous to eradicate it or kill the …

Streptococcus mutans and Candida albicans exhibit strong cariogenicity through cross-
kingdom biofilm formation during the pathogenesis of dental caries. Caffeic acid phenethyl …

The cross-kingdom interactions between Candida albicans and Streptococcus mutans have
played important roles in early childhood caries (ECC). However, the key pathways of C …

Streptococcus mutans (S. mutans) and Candida albicans (C. albicans) are prominent
microbes associated with rapid and aggressive caries. In the present study, we investigated …