Long COVID science, research and policy

Z Al-Aly, H Davis, L McCorkell, L Soares… - Nature medicine, 2024 - nature.com
Long COVID represents the constellation of post-acute and long-term health effects caused
by SARS-CoV-2 infection; it is a complex, multisystem disorder that can affect nearly every …

Laboratory findings and biomarkers in Long COVID: what do we know so far? Insights into epidemiology, pathogenesis, therapeutic perspectives and challenges

D Tsilingiris, NG Vallianou, I Karampela… - International Journal of …, 2023 - mdpi.com
Long COVID (LC) encompasses a constellation of long-term symptoms experienced by at
least 10% of people after the initial SARS-CoV-2 infection, and so far it has affected about 65 …

Post-acute sequelae of SARS-CoV-2 cardiovascular symptoms are associated with trace-level cytokines that affect cardiomyocyte function

JE Sinclair, C Vedelago, FJ Ryan, M Carney… - Nature …, 2024 - nature.com
An estimated 65 million people globally suffer from post-acute sequelae of COVID-19
(PASC), with many experiencing cardiovascular symptoms (PASC-CVS) like chest pain and …

Mild to moderate post-COVID-19 alters markers of lymphocyte activation, exhaustion, and immunometabolic responses that can be partially associated by physical …

BSA Silva, T Pereira, LG Minuzzi, CS Padilha… - Frontiers in …, 2023 - frontiersin.org
Aim This study aimed to evaluate if physical activity is associated with systemic and cellular
immunometabolic responses, in young adults after mild-to-moderate COVID-19 infection …

Characterizing long-COVID brain fog: A retrospective cohort study

GY Lam, RW Damant, G Ferrara, RK Lim… - Journal of …, 2023 - Springer
Background Long COVID or post-COVID condition (PCC) is a common complication
following acute COVID-19 infection. PCC is a multi-systems disease with neurocognitive …

Blood biomarkers of long COVID: A systematic review

C Thomas, MA Faghy, C Chidley, BE Phillips… - Molecular Diagnosis & …, 2024 - Springer
Background Long coronavirus disease (COVID; LC) affects millions of people worldwide.
The exact mechanisms which result in a broad, undulating and detrimental symptom profile …

[HTML][HTML] Epstein–Barr virus-acquired immunodeficiency in myalgic encephalomyelitis—Is it present in long COVID?

M Ruiz-Pablos, B Paiva, A Zabaleta - Journal of Translational Medicine, 2023 - Springer
Both myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS) and long COVID
(LC) are characterized by similar immunological alterations, persistence of chronic viral …

Immune activation and immune-associated neurotoxicity in Long-COVID: A systematic review and meta-analysis of 103 studies comprising 58 cytokines/chemokines …

AF Almulla, Y Thipakorn, B Zhou, A Vojdani… - Brain, Behavior, and …, 2024 - Elsevier
Background Multiple studies have shown that Long COVID (LC) disease is associated with
heightened immune activation, as evidenced by elevated levels of inflammatory mediators …

Long COVID: molecular mechanisms and detection techniques

A Constantinescu-Bercu, A Lobiuc… - International Journal of …, 2023 - mdpi.com
Long COVID, also known as post-acute sequelae of SARS-CoV-2 infection (PASC), has
emerged as a significant health concern following the COVID-19 pandemic. Molecular …

Early immune factors associated with the development of post-acute sequelae of SARS-CoV-2 infection in hospitalized and non-hospitalized individuals

JM Leung, MJ Wu, P Kheradpour, C Chen… - Frontiers in …, 2024 - frontiersin.org
Background Infection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
can lead to post-acute sequelae of SARS-CoV-2 (PASC) that can persist for weeks to years …